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The Relationship Between Serum PSA Levels and WBC, Delta Neutrophil Index (DNI) and Other Hematological Parameters

Sponsor
Hisar Intercontinental Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT05399940
Collaborator
(none)
250
Enrollment
1
Location
52.6
Actual Duration (Months)
4.8
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Purpose:

To find the correlation between hemogram parameters and Delta Neutrophil Index(DNI) and Serum PSA in patients presenting with the diagnosis of acute prostatitis.

Material-Metod: Serum PSA levels and hemogram parameters of patients who came to the urology outpatient clinic in January 2018 and May 2022 and were diagnosed with prostatitis were collected retrospectively.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Serum PSA,Delta Neutrophil Index(DNI),WBC

Detailed Description

Serum PSA levels and hemogram parameters of patients who came to the urology outpatient clinic in January 2018 and May 2022 and were diagnosed with prostatitis were collected retrospectively.

WBC, neutrophil, lymphocyte, neutrophil-lymphocyte ratio, delta neutrophil index (DNI), PLT, RDW, and MPV values were determined in the Hemogram Parameters. Serum Total PSA and Free PSA values of the patients were also checked. Urine culture, urinary ultrasound, and antibiotic therapy

Study Design

Study Type:
Observational [Patient Registry]
Actual Enrollment :
250 participants
Observational Model:
Cohort
Time Perspective:
Other
Official Title:
The Relationship Between Serum PSA Levels and WBC, Delta Neutrophil Index (DNI) and Other Hematological Parameters
Actual Study Start Date :
Jan 1, 2018
Actual Primary Completion Date :
May 1, 2022
Actual Study Completion Date :
May 20, 2022

Arms and Interventions

Arm Intervention/Treatment
Group 1

:PSA<4 ng/mL

Diagnostic Test: Serum PSA,Delta Neutrophil Index(DNI),WBC
Urine culture, prostate volume
Other Names:
  • MPV,NLR,RDW

    		•
    Group 2

    PSA>4 ng/mL

    Diagnostic Test: Serum PSA,Delta Neutrophil Index(DNI),WBC
    Urine culture, prostate volume
    Other Names:
  • MPV,NLR,RDW

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Area Under the Plasma Concentration Versus Time Curve (AUC) [4 years]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 90 Years
    Sexes Eligible for Study:
    Male
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    Acute prostatitis Male

    -

    Exclusion Criteria:

    Prostate cancer Chronic prostatitis Other Urinary infections,

    -

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Basri Cakiroglu Istanbul Turkey 34768

    Sponsors and Collaborators

    • Hisar Intercontinental Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Basri Cakiroglu, Ass. Prof., Hisar Intercontinental Hospital
    ClinicalTrials.gov Identifier:
    NCT05399940
    Other Study ID Numbers:
    • 22/5-27
    First Posted:
    Jun 1, 2022
    Last Update Posted:
    Jun 1, 2022
    Last Verified:
    May 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Yes
    Plan to Share IPD:
    Yes
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Basri Cakiroglu, Ass. Prof., Hisar Intercontinental Hospital
    prostatit
    Additional relevant MeSH terms:
    Prostatic Diseases

    Study Results

    No Results Posted as of Jun 1, 2022