Clincosm LogoSign in Get a demo

Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

Sponsor
Hillel Yaffe Medical Center (Other)
Overall Status
Unknown status
CT.gov ID
NCT00419627
Collaborator
Technion, Israel Institute of Technology (Other)
160
Enrollment
1
Location

Study Details

Study Description

Brief Summary

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

    Study Design

    Study Type:
    Observational
    Observational Model:
    Natural History
    Time Perspective:
    Prospective
    Official Title:
    Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.
    Study Start Date :
    Feb 1, 2007

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      All
      Inclusion Criteria:
      • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas
      Exclusion Criteria:

      • Withdrawal of consent

      • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Hillel Yaffe Medical Center Hadera Israel 38100

      Sponsors and Collaborators

      • Hillel Yaffe Medical Center
      • Technion, Israel Institute of Technology

      Investigators

      • Principal Investigator: Itamar Ashkenazi, M.D., Hillel Yaffe Medical Center

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00419627
      Other Study ID Numbers:
      • ProtHYMC
      First Posted:
      Jan 8, 2007
      Last Update Posted:
      Jan 8, 2007
      Last Verified:
      Jan 1, 2007
      Keywords provided by , ,
      proteomics of solid tumors
      Additional relevant MeSH terms:
      Neoplasms
      Breast Neoplasms
      Colorectal Neoplasms
      Pancreatic Neoplasms
      Stomach Neoplasms

      Study Results

      No Results Posted as of Jan 8, 2007