The Effects of Weight Loss on Psoriatic Arthritis
Study Details
Study Description
Brief Summary
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into "diet", "diet+bety", and "control" groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms.
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Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups.
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Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian.
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BETY exercise training will be given by a registered physiotherapist.
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The subjects will be followed for 12 weeks.
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Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: diet group weight loss diet intervention for 12 weeks |
Behavioral: diet and biopsychosocial exercise intervention
dietary intervention: biopsychosocial exercise intervention:
|
Experimental: diet+bety group weight loss diet intervention for 12 weeks and exercise-based biopsychosocial approach (Cognitive Exercise Therapy Approach-BETY) intervention for 12 weeks |
Behavioral: diet and biopsychosocial exercise intervention
dietary intervention: biopsychosocial exercise intervention:
|
No Intervention: control group no intervention, control |
Outcome Measures
Primary Outcome Measures
- Weight Loss [At the end of 3 months]
BMI (kilogram/metre2(kg/m2))
- DAPSA score [At the end of 3 months]
The score ranges from 0 to 50 points, with increased score reflect more discomfort
Secondary Outcome Measures
- Quality of Life Score [At the end of 3 months]
The score ranges from 0 to 100 points, with increased score reflecting improved quality of life
Eligibility Criteria
Criteria
Inclusion Criteria:
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overweight/obese
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diagnosed with PSA
Exclusion Criteria
- pregnancy or lactation
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Sümeyra Öteleş | Ankara | Turkey | 06100 |
Sponsors and Collaborators
- Hacettepe University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- HU-SO-2022