Corneal Topographic Changes After Pterygium Surgery
Sponsor
Sohag University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05026307
Collaborator
(none)
25
1
1
7.6
3.3
Study Details
Study Description
Brief Summary
The purpose of the study is to assess the corneal topographic changes after primary pterygium surgery
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Prospective interventional comparative study . This study will be conducted on eyes with primary pterygium before and after successful excision in department of ophthalmology, Sohag university hospital to assess the corneal topographic changes using pentacam .
Postoperative evaluation will be scheduled for one month ,three and six months postoperative.
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
25 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Corneal Topographic Changes After Pterygium Surgery
Actual Study Start Date
:
Jun 15, 2021
Anticipated Primary Completion Date
:
Dec 1, 2021
Anticipated Study Completion Date
:
Feb 1, 2022
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Pterygium Simple surgical excision of pterygium withe bare sclera |
Procedure: Excision of pterygium
Simple surgical excision of pterygium with bare sclera
|
Outcome Measures
Primary Outcome Measures
- Changes in corneal topography [One month, three and six months postoperative]
Detection of changes in corneal topography using Pentacam
Eligibility Criteria
Criteria
Ages Eligible for Study:
20 Years
to 70 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- patients with primary pterygium
Exclusion Criteria:
-
patients with recurrent pterygium
-
patients with primary pterygium with other ocular pathologies.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Sohag | Sohag | Egypt | 82511 |
Sponsors and Collaborators
- Sohag University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Di Girolamo N, Chui J, Coroneo MT, Wakefield D. Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases. Prog Retin Eye Res. 2004 Mar;23(2):195-228. Review.
- Moran DJ, Hollows FC. Pterygium and ultraviolet radiation: a positive correlation. Br J Ophthalmol. 1984 May;68(5):343-6.
- Nangia V, Jonas JB, Nair D, Saini N, Nangia P, Panda-Jonas S. Prevalence and associated factors for pterygium in rural agrarian central India. The central India eye and medical study. PLoS One. 2013 Dec 4;8(12):e82439. doi: 10.1371/journal.pone.0082439. eCollection 2013.
- Xu Z, Li W, Jiang J, Zhuang X, Chen W, Peng M, Wang J, Lu F, Shen M, Wang Y. Characteristic of entire corneal topography and tomography for the detection of sub-clinical keratoconus with Zernike polynomials using Pentacam. Sci Rep. 2017 Nov 28;7(1):16486. doi: 10.1038/s41598-017-16568-y.
Responsible Party:
Sara Ahmed Abdelraheem,
Principle investigator,
Sohag University
ClinicalTrials.gov Identifier:
NCT05026307
Other Study ID Numbers:
- Soh-Med-21-06-03
First Posted:
Aug 30, 2021
Last Update Posted:
Aug 30, 2021
Last Verified:
Aug 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: