Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants
Study Details
Study Description
Brief Summary
Investigators hypothesized that lung ultrasound-assisted recruitment maneuver would be beneficial in mechanically ventilated infants compared to those who did not receive lung ultrasound and alveolar recruitment maneuver.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Placebo Comparator: Control No intervention during the perioperative period. Perform lung ultrasound twice only for the diagnostic purpose after the endotracheal intubation and and at the end of surgery. |
Device: Lung ultrasound
Lung ultrasound on both hemithorax in supine position
|
| Active Comparator: Alveolar recruitment Perform lung ultrasound twice during the perioperative period after the endotracheal intubation and and at the end of surgery. Conduct alveolar recruitment maneuver after first lung ultrasound assessment. |
Device: Lung ultrasound
Lung ultrasound on both hemithorax in supine position
|
Outcome Measures
Primary Outcome Measures
- Postoperative incidence of pulmonary atelectasis [within the first day after the surgery]
Secondary Outcome Measures
- Intraoperative incidence of pulmonary atelectasis after endotracheal intubation [from the moment of endotracheal intubation until the end of surgery, up to 6 hours]
- Intraoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value) [from the induction of general anesthesia until the end of the surgery, up to 6 hours]
- Postoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value) [within the first day after the surgery]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Minor surgery less than 2 hours under general anesthesia
-
Mechanically ventilated after endotracheal intubation
Exclusion Criteria:
-
History of surgery on the lungs
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Laparoscopic surgery
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Abnormal preoperative chest radiograph findings including atelectasis, pneumothorax, pleural effusion, and pneumonia
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Considered inappropriate by the investigator
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Seoul National University Hospital | Seoul | Korea, Republic of | 110-744 |
Sponsors and Collaborators
- Seoul National University Hospital
Investigators
- Principal Investigator: Jin-Tae Kim, Seoul National University Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- Acosta CM, Maidana GA, Jacovitti D, Belaunzarán A, Cereceda S, Rae E, Molina A, Gonorazky S, Bohm SH, Tusman G. Accuracy of transthoracic lung ultrasound for diagnosing anesthesia-induced atelectasis in children. Anesthesiology. 2014 Jun;120(6):1370-9. doi: 10.1097/ALN.0000000000000231.
- Ashton-Cleary DT. Is thoracic ultrasound a viable alternative to conventional imaging in the critical care setting? Br J Anaesth. 2013 Aug;111(2):152-60. doi: 10.1093/bja/aet076. Epub 2013 Apr 12. Review.
- Kiley S, Cassara C, Fahy BG. Lung ultrasound in the intensive care unit. J Cardiothorac Vasc Anesth. 2015 Feb;29(1):196-203. doi: 10.1053/j.jvca.2014.10.017. Review.
- Lutterbey G, Wattjes MP, Doerr D, Fischer NJ, Gieseke J Jr, Schild HH. Atelectasis in children undergoing either propofol infusion or positive pressure ventilation anesthesia for magnetic resonance imaging. Paediatr Anaesth. 2007 Feb;17(2):121-5.
- Magnusson L, Spahn DR. New concepts of atelectasis during general anaesthesia. Br J Anaesth. 2003 Jul;91(1):61-72. Review.
- Tusman G, Böhm SH, Tempra A, Melkun F, García E, Turchetto E, Mulder PG, Lachmann B. Effects of recruitment maneuver on atelectasis in anesthetized children. Anesthesiology. 2003 Jan;98(1):14-22.
- H-1509-063-703