Effects of M-TAPA Block on Pulmonary Functions

Zonguldak Bulent Ecevit University (Other)
Overall Status
Active, not recruiting
CT.gov ID

Study Details

Study Description

Brief Summary

Adequate postoperative analgesia is difficult to achieve in patients undergoing laparoscopic sleeve gastrectomy (LSG). Epidural anesthesia is technically difficult due to subcutaneous fat, which increases the risk of serious complications. Moreover, patients in this condition often have comorbidities that require anticoagulation therapy. Although ultrasound-guided Transversus Abdominis Plane (TAP) block may be useful, it is still controversial.

Recently, modified thoracoabdominal nerve block via perichondrial approach (M-TAPA) has been reported as a new and promising technique that provides effective analgesia in the anterior and lateral thoracoabdominal wall.

The most common reason for hospitalization after laparoscopic surgery is pain after nausea and vomiting. In addition, superficial and tachypneic breathing resulting from the patient's inability to breathe deeply with pain causes closure of small airways and increase in intrapulmonary shunts, resulting in hypoxia. Postoperative pain management is important not only to prevent pain but also to reduce pulmonary complications that may occur due to changes in lung function and to reduce mortality and morbidity by controlling the stress response.

In this study, we investigated the effect of modified thoracoabdominal nerve block via perichondrial approach (M-TAPA) on pulmonary function in patients undergoing laparoscopic bariatric surgery under general anesthesia.

Condition or Disease Intervention/Treatment Phase
  • Procedure: Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA)

Study Design

Study Type:
Observational [Patient Registry]
Actual Enrollment :
1 participants
Observational Model:
Time Perspective:
Official Title:
Effects of M-TAPA Block on Postoperative Pulmonary Functions in Laparoscopic Bariatric Surgery: A Randomized Controlled Study
Actual Study Start Date :
Oct 20, 2023
Anticipated Primary Completion Date :
Apr 20, 2024
Anticipated Study Completion Date :
May 20, 2024

Arms and Interventions

Arm Intervention/Treatment
Group M-TAPA

Procedure: Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA)
application local anesthetic between internal oblique and transversus abdominis muscle at the level of 10th costal cartilage

Group Control

Outcome Measures

Primary Outcome Measures

  1. FEV1/FVC ratio [during the procedure]

    Pulmonary function

Secondary Outcome Measures

  1. Numerical Rating Scale [during the procedure]

    pain assessment tool

  2. opioid consumption [24 hours after surgery]

    need of opioid postoperatively

Eligibility Criteria


Ages Eligible for Study:
18 Years to 65 Years
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Inclusion Criteria:
  • Between 18-65 years old

  • ASA I-II-III risk group

  • Patients whose approval was obtained through an informed consent form

  • Will undergo laparoscopic bariatric surgery

  • Patients who will cooperate for the PFT test

Exclusion Criteria:
  • <18 years and >65 years

  • ASA ≥ IV

  • 50% below the expected value in SFT

  • Known diaphragmatic paralysis

  • Having had a myocardial infarction within 1 month

  • Dementia or confusion

  • Lack of cooperation

  • Those with respiratory disease

  • Congestive heart failure

  • Unstable hypertension

  • Had thoracoabdominal surgery

Contacts and Locations


Site City State Country Postal Code
1 Zonguldak Bülent Ecevit University Medicine Faculty Zonguldak Kozlu Turkey 67600

Sponsors and Collaborators

  • Zonguldak Bulent Ecevit University


None specified.

Study Documents (Full-Text)

None provided.

More Information


None provided.
Responsible Party:
Çağdaş Baytar, medical doctor, Zonguldak Bulent Ecevit University
ClinicalTrials.gov Identifier:
Other Study ID Numbers:
  • 2023/04-4
First Posted:
Nov 28, 2023
Last Update Posted:
Nov 28, 2023
Last Verified:
Nov 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD:
Studies a U.S. FDA-regulated Drug Product:
Studies a U.S. FDA-regulated Device Product:
Keywords provided by Çağdaş Baytar, medical doctor, Zonguldak Bulent Ecevit University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 28, 2023