Pulse and Constitution of Pregnant Women
Study Details
Study Description
Brief Summary
The present project plans to detect pregnant pulses using this portable ANS (autonomic nervous system) Watch connected to a laptop. One hundred pregnant women and 100 non-pregnant women will be recruited.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
ANS(autonomic nervous system) Watch has been developed as to detect pulse waves using a pressure detector. It is used to measured cardiovascular indices, including cardiac output, and vessel stiffness. ANSWatch is developed to apply to the prediction of traditional Chinese medicine (TCM) pulses, such as the wiry pulse. There are 28 types of pulses in TCM. Among them, the slippery pulse is the most commonly seen pulse in pregnant women. The present project plans to detect pregnant pulses using this portable ANSWatch connected to a laptop. One hundred pregnant women and 100 non-pregnant women will be recruited. After taking the indices of the subjects, a neural network is designed to provide the prediction for pregnancy constitution, pregnancy pulse and slippery pulse in pregnant women.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Pregnant pregnant women |
Diagnostic Test: ANS Watch
ANS Watch will be used to record the pulse waves
Constitution questionnaire will be used to measure the constitution type
Other Names:
|
| Non-pregnant non-pregnant women |
Diagnostic Test: ANS Watch
ANS Watch will be used to record the pulse waves
Constitution questionnaire will be used to measure the constitution type
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Pulse waves [Day 1]
indices of the pulse waves measured by ANSWatch (https://www.taiwanscientific.com.tw/%E5%BF%83%E5%BE%8B%E5%A4%A7%E5%B8%ABanswatch). A neural network is designed to provide the prediction for pregnancy pulse.
Secondary Outcome Measures
- Constitution [Day 1]
Nine constitutions will be measured using the "Nine constitution Questionnaire" (in Chinese). This questionnaire defines whether subjects have Yin-deficiency, Yang-deficiency, Qi-deficiency, Phlegm-dampness, Dampness-heat, Special dialesis, Blood-stasis, Qi-depression, and Neuture constitutions.
Eligibility Criteria
Criteria
Inclusion Criteria:
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nonpregnant females and singleton pregnant females aged 20 - 45 years;
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no estrogen, progesterone, or ovulation inducing medications were in the past six months
Exclusion Criteria:
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active heart disease, liver disease, kidney disease, or thyroid disease;
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any chronic disease which needs medication
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smoking, drug abuse, or alcohol abuse;
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psychiatric disorders or impaired cognitive function;
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taking Chinese medicine or western medicine in three months;
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Acute conditions currently, such as gastroenteritis, upper airway infection, acute attach of asthma, etc.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Shan-Yu Su | Taichung | Taiwan | 404 |
Sponsors and Collaborators
- China Medical University Hospital
Investigators
- Principal Investigator: Shan-Yu Su, M.D., China Medical University, China
Study Documents (Full-Text)
None provided.More Information
Publications
- Khalil SF, Mohktar MS, Ibrahim F. The theory and fundamentals of bioimpedance analysis in clinical status monitoring and diagnosis of diseases. Sensors (Basel). 2014 Jun 19;14(6):10895-928. doi: 10.3390/s140610895. Review.
- Pollonini L, Padhye NS, Re R, Torricelli A, Simpson RJ, Dacso CC. Pulse transit time measured by photoplethysmography improves the accuracy of heart rate as a surrogate measure of cardiac output, stroke volume and oxygen uptake in response to graded exercise. Physiol Meas. 2015 May;36(5):911-24. doi: 10.1088/0967-3334/36/5/911. Epub 2015 Apr 9.
- Sanghavi M, Rutherford JD. Cardiovascular physiology of pregnancy. Circulation. 2014 Sep 16;130(12):1003-8. doi: 10.1161/CIRCULATIONAHA.114.009029. Review.
- Zhang YL, Zheng YY, Ma ZC, Sun YN. Radial pulse transit time is an index of arterial stiffness. Hypertens Res. 2011 Jul;34(7):884-7. doi: 10.1038/hr.2011.41. Epub 2011 May 19.
- CMUH110-REC2-144