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Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01719393
Collaborator
(none)
100
Enrollment
1
Location
13
Duration (Months)
7.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Our hypothesis is that radial arterial pulse may reflect the severity and airway function in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with airy inflammation an lung funtion in asthmatics.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The microcirculation is directly involved in the cellular matabolism and homeostasis. Our hypothesis is that radial arterial pulse spectrum may reflect the airway condition in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with lung function, asthma control status,exhaled nitric oxide, and metabolites in the exhaed breath condensates.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    100 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath
    Study Start Date :
    Nov 1, 2012
    Anticipated Primary Completion Date :
    Nov 1, 2013
    Anticipated Study Completion Date :
    Dec 1, 2013

    Outcome Measures

    Primary Outcome Measures

    1. Pulse spectral analysis [one year]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Meet the diagnostic criteria of GINA guideline asthma patients
    Exclusion Criteria:

    • Cancer or immune impaired patients;

    • pack-year smoking> 5;

    • long-term ventilator-dependent patients

    • Control group: 30 age matched healthy controls

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Taiwan University Hospital Taipei Taiwan

    Sponsors and Collaborators

    • National Taiwan University Hospital

    Investigators

    • Principal Investigator: Ping-Hung Kuo, National Taiwan University Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Taiwan University Hospital, M.D., National Taiwan University Hospital
    ClinicalTrials.gov Identifier:
    NCT01719393
    Other Study ID Numbers:
    • 201207062RIC
    First Posted:
    Nov 1, 2012
    Last Update Posted:
    Nov 1, 2012
    Last Verified:
    Oct 1, 2012
    Keywords provided by National Taiwan University Hospital, M.D., National Taiwan University Hospital
    Asthma
    Pulse spectrum analysis
    lung function
    exhaled nitric oxide
    metabolites
    exhaled breath condensate
    Additional relevant MeSH terms:
    Asthma

    Study Results

    No Results Posted as of Nov 1, 2012