QUATRO: Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated With Antithrombotics for an Ischemic Stroke.

Sponsor

Hospices Civils de Lyon (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05741593

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

2.5

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

Condition or Disease	Intervention/Treatment	Phase
Stroke	Other: Analysis of the verbatim from the transcription of the recorded interviews.

Detailed Description

Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. The probability of stroke recurrence is high: about 25% the first year , and 30 to 40% in the 5 years following the stroke. Recurrent strokes are responsible for significant disability, institutionalization, major neurocognitive disorders, and death.

In order to reduce the risk of stroke recurrence, multiple secondary prevention strategies have demonstrated their effectiveness, such as the prescription of drugs (in particular statins and antithrombotics), the establishment of a balanced diet, the practice of an activity physical, or even tobacco addiction.

However, the effectiveness of these strategies is optimal if and only if patients adhere to them.

In addition, previous studies have focused on the brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

In elderly patients, other obstacles could have been identified by specific studies, such as cognitive, sensory, functional disorders or even isolation.

Study Design

Study Type:

Observational

Anticipated Enrollment :

30 participants

Observational Model:

Other

Time Perspective:

Prospective

Official Title:

Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated With Antithrombotics for an Ischemic Stroke.

Anticipated Study Start Date :

Apr 1, 2023

Anticipated Primary Completion Date :

Apr 1, 2024

Anticipated Study Completion Date :

Apr 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
Patients having had a stroke elderly patients previously treated with an antithrombotic and admitted to hospital for an ischemic stroke	Other: Analysis of the verbatim from the transcription of the recorded interviews. recorded semi-structured interviews between the patients and the pharmacist

Arm

Intervention/Treatment

Patients having had a stroke

elderly patients previously treated with an antithrombotic and admitted to hospital for an ischemic stroke

Other: Analysis of the verbatim from the transcription of the recorded interviews.

recorded semi-structured interviews between the patients and the pharmacist

Outcome Measures

Primary Outcome Measures

Analysis of the verbatim from the transcription of the recorded interviews. [one year]
Describing the content of discussions, relating to antithrombotic treatment for secondary prevention, between elderly patients previously treated with antithrombotics and admitted to hospital for an ischemic stroke and a pharmacist

Secondary Outcome Measures

Analysis of verbatim statements from the transcription of recorded interviews on patients' representations and beliefs regarding antithrombotics [15 to 60 minutes per patient]
Exploring patients' representations and beliefs regarding antithrombotics before and after the onset of stroke or recurrence of stroke
Analysis of verbatim statements from the transcription of recorded interviews on patients' medication adherence to antithrombotics [15 to 60 minutes per patient]
Explore patients' medication adherence to antithrombotics before the onset of stroke or recurrence of stroke
Analysis of verbatim statements from the transcription of recorded interviews on the impact of the occurrence of stroke or recurrence of stroke on medication adherence [15 to 60 minutes per patient]
Explore the impact of stroke occurrence or stroke recurrence on patient medication adherence (including motivation, ambivalence, confidence in medication benefits)
Analysis of verbatim statements from the transcription of recorded interviews on the obstacles and levers to medication adherence [15 to 60 minutes per patient]
Identify the barriers and levers to drug adherence with antithrombotics

Eligibility Criteria

Criteria

Ages Eligible for Study:

65 Years to 100 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

Patients aged 65 and over
Patients hospitalized for an ischemic stroke or a recurrence of ischemic stroke, already being treated with an antithrombotic treatment (antiplatelet agent or anticoagulant ) prior to the stroke
Patients living at home and with a plan to return home.
Patients who did not object to the study and who gave their consent for the recording of the interview

Exclusion Criteria:

Patients with cognitive disorders or stroke sequelae that do not allow a semi-directive interview to be carried out (at medical discretion).
Non-French speaking patients