The Quality of Life in Individuals With Parkinson's Disease

Sponsor

Pamukkale University (Other)

Overall Status

Completed

CT.gov ID

NCT05906693

Collaborator

(none)

Enrollment

Location

30.4

Actual Duration (Months)

1.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.

Condition or Disease	Intervention/Treatment	Phase
Parkinson Disease Tremor Functionality	Other: Quality of life Other: Upper limb functionality Other: Grip and pinch strength Other: Tremor amplitude Other: Depression and anxiety levels Other: Clinical manifestations

Detailed Description

Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.

Study Design

Study Type:

Observational

Actual Enrollment :

52 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

A Cross-sectional Study - The Quality of Life in Individuals With Parkinson's Disease: Is it Related to Functionality and Tremor Severity?

Actual Study Start Date :

Jan 1, 2019

Actual Primary Completion Date :

Nov 20, 2020

Actual Study Completion Date :

Jul 13, 2021

Outcome Measures

Primary Outcome Measures

Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale [1 year]
The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale. Used for the evaluation of clinical manifestations of Parkinson's disease. The scale consists of 4 subscales: the first part is Non-Motor Aspects of Experiences of Daily Living (13), the second part is Motor Aspects of Experiences of Daily Living (13), the third part is Motor Examination (33), and the fourth part is Motor Complications (6). The total number of items in the scale is 65. The minimum score is 0. The maximum MDS-UPDRS score is higher, given the additional items and scores for each body area, with a maximum score of 272. Higher scores indicate greater impact of Parkinson Disease symptoms.
Hospital Anxiety and Depression Scale [1 year]
The Hospital Anxiety and Depression Scale aims to measure symptoms of anxiety and depression and consists of 14 items, seven items for the anxiety subscale (Hospital Anxiety and Depression Scale Anxiety) and seven for the depression subscale (Hospital Anxiety and Depression Scale Depression). Each item is scored on a response-scale with four alternatives ranging between 0 and 3. After adjusting for six items that are reversed scored, all responses are summed to obtain the two subscales. Both depression and anxiety subheadings are scored between 0 and 21. Higher scores indicate greater levels of anxiety or depression. Cut-off scores are 8-10 for doubtful cases and ≥11 for definite cases.
Parkinson's Disease Quality of Life Questionnaire (PDQ-39) [1 year]
Used to assess the quality of life of Parkinson's patients
Electromyography [1 year]
Used to assess the tremor amplitude of Parkinson's patients
Nine-Hole Peg Test [1 year]
Used to assess the upper limb functionality of Parkinson's patients
Dynamometer [1 year]
Used to assess the grip and pinch strength of Parkinson's patients

Eligibility Criteria

Criteria

Ages Eligible for Study:

40 Years to 80 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Definite diagnosis of idiopathic Parkinson Disease
Age between 40 and 80 years
Being literate
Having a grade between 1-4 from the Modified Hoehn and Yahr Scale
Having a score lower than 11 in Hospital Anxiety and Depression Scale

Exclusion Criteria:

Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity
Using antidepressants
Having vision loss
Deep brain stimulation