RADIAL: Radial Artery Access
Study Details
Study Description
Brief Summary
This is an imaging investigation to assess the factors effecting radial artery diameter:
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Patient demographics
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Diameter change post standard care preparation
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
There are significant benefits to radial access intervention, namely superior mortality and morbidity Vs femoral access. In addition, there is significant patient preference and reduced nursing time post procedure in comparison to femoral access supporting day case practice.
Interventional oncology routinely involves repeated procedures therefore patient preference is a key factor in access choice. This again supports day case practice with significant patient preference also noted.
The clinical application of the study is to allow a broader spectrum of procedures to be performed via radial access. Currently due to a limited data available on factors effecting radial artery diameter practice there is a restriction on sheath size use. This limits the procedures that can be performed via this route. By assessing the diameter and factors which increase the vessel, larger access sheaths can be used opening up the procedure portfolio including neuro-interventional procedures and coeliac axis stenting. This will allow these procedures to be performed with added benefits of improved mortality/morbidity in addition patient preference.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| All patients All patients undergoing Radial Artery Access requiring interventional radiology. |
Procedure: Radial Artery Access
The radial artery is stabilized between the thumb and forefinger of the left hand and 1 to 2 mL of subcutaneous lidocaine is used to create a wheal over the zone of planned entry.
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Outcome Measures
Primary Outcome Measures
- Radial Artery diameter [Before the procedure, during the procedure, and immediately after the procedure]
The change in RA diameter during a standard of care RA access procedure performed by an interventional Radiologist before the procedure, during the procedure and immediately after the procedure and how this compares to patient demographics.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Aged 18 or over
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All patients undergoing Radial Artery Access requiring interventional radiology.
Exclusion Criteria:
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Prior history of radial artery occlusion
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Prior history of stroke
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Need for future dialysis access creation or preservation of upper extremity vasculature for patients with chronic kidney disease
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- The Christie NHS Foundation Trust
- Terumo UK Ltd.
Investigators
- Principal Investigator: Pavan Najran, Dr, The Christie NHS Foundation Trust
Study Documents (Full-Text)
None provided.More Information
Publications
- Beyer AT, Ng R, Singh A, Zimmet J, Shunk K, Yeghiazarians Y, Ports TA, Boyle AJ. Topical nitroglycerin and lidocaine to dilate the radial artery prior to transradial cardiac catheterization: a randomized, placebo-controlled, double-blind clinical trial: the PRE-DILATE Study. Int J Cardiol. 2013 Oct 3;168(3):2575-8. doi: 10.1016/j.ijcard.2013.03.048. Epub 2013 Apr 10.
- Boyer N, Beyer A, Gupta V, Dehghani H, Hindnavis V, Shunk K, Zimmet J, Yeghiazarians Y, Ports T, Boyle A. The effects of intra-arterial vasodilators on radial artery size and spasm: implications for contemporary use of trans-radial access for coronary angiography and percutaneous coronary intervention. Cardiovasc Revasc Med. 2013 Nov-Dec;14(6):321-4. doi: 10.1016/j.carrev.2013.08.009. Epub 2013 Oct 2.
- CFTsp219