Radiation Planning Study for High Grade Brain Tumors

Sponsor

University of Cincinnati (Other)

Overall Status

Completed

CT.gov ID

NCT01191346

Collaborator

(none)

Enrollment

Location

Duration (Months)

0.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this research study is to see if a higher strength MRI procedure provides better images to use in planning radiation treatments for patients with brain tumors in the future.

Condition or Disease	Intervention/Treatment	Phase
High Grade Glioma	Other: 3T MRI

Study Design

Study Type:

Observational

Actual Enrollment :

24 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

3T Versus 1.5T MR Approaches in Target Definition for Malignant Gliomas: Is There a Significant Difference in Tumor Extent and Radiation Treatment Volume?

Study Start Date :

Jun 1, 2010

Actual Primary Completion Date :

Mar 1, 2013

Actual Study Completion Date :

Mar 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
3T MRI Patients receiving 3T MRI	Other: 3T MRI 3T MRI in addition to standard 1.5T MRI for treatment planning

Arm

Intervention/Treatment

3T MRI

Patients receiving 3T MRI

Other: 3T MRI

3T MRI in addition to standard 1.5T MRI for treatment planning

Outcome Measures

Primary Outcome Measures

Treatment volume [1 year average]
To assess the difference in treatment volume for radiation planning in gliomas as calculated using 1.5T versus 3T magnets

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Histologically confirmed, newly diagnosed Grade III-IV glioma
Planning to undergo radiation therapy

Exclusion Criteria:

Grade I or II glioma
Patients unable to undergo MRI imaging

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Cincinnati	Cincinnati	Ohio	United States	45219

Sponsors and Collaborators

University of Cincinnati

Investigators

Principal Investigator: Jessica Guarnaschelli, MD, University of Cincinnati

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Alison Kastl, BS, CCRC, Director of Clinical Trials, University of Cincinnati

ClinicalTrials.gov Identifier:

NCT01191346

Other Study ID Numbers:

BTC-G1

First Posted:

Aug 30, 2010

Last Update Posted:

Aug 22, 2017

Last Verified:

Dec 1, 2014

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Additional relevant MeSH terms:

Glioma

Study Results

No Results Posted as of Aug 22, 2017