RADI-S: Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Other)
Overall Status
Completed
CT.gov ID
NCT06044961
Collaborator
(none)
80
214.4
Study Details
Study Description
Brief Summary
Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.
The study aims to apply radiomics for the prediction of response to neoadjuvant therapy.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
80 participants
Observational Model:
Other
Time Perspective:
Retrospective
Official Title:
Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Study Start Date
:
Jan 1, 2005
Actual Primary Completion Date
:
Aug 30, 2022
Actual Study Completion Date
:
Nov 15, 2022
Outcome Measures
Primary Outcome Measures
- Use of radiomics [1 month]
Apply radiomics for predicting response to neoadjuvant therapy.
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Patients with locally advanced stomach cancer undergoing neoadjuvant chemotherapy and gastrectomy between January 2005 and August 2022
Exclusion Criteria:
-
Siewert 1 tumors;
-
Patients who have received neoadjuvant with the addition of a biological drug;
-
Patients who have received radiotherapy;
-
Patients without staging CT scan or with insufficient image quality in terms of phases performed, pixel spacing, slide thickness (mandatorily: > 5 mm) or artefacts.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Agnes Annamaria,
MD,
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
ClinicalTrials.gov Identifier:
NCT06044961
Other Study ID Numbers:
- 5297
First Posted:
Sep 21, 2023
Last Update Posted:
Sep 21, 2023
Last Verified:
Sep 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Agnes Annamaria,
MD,
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Additional relevant MeSH terms: