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Ramanspectroscopy in Barrett's Esophagus

Sponsor
Mayo Clinic (Other)
Overall Status
Completed
CT.gov ID
NCT00588575
Collaborator
National Institutes of Health (NIH) (NIH)
119
Enrollment
1
Location
36
Duration (Months)
3.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study is being done to see if a new device, called near-infrared Raman spectroscopy, can provide similar information as that obtained from taking biopsies of the lining of your Barrett's esophagus

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    In the search for means to enhance the surveillance of BE, optical spectroscopy is emerging as a candidate with high potential. Optical spectroscopic techniques measure specific light-tissue interactions, such as fluorescence, elastic scattering, and Raman (inelastic) scattering, which provide objective and quantitative diagnostic information about the molecular and/or structural status of tissue. Moreover, optical spectroscopy has the capacity to identify tissue pathology in situ in a rapid and non-destructive fashion. Among the optical spectroscopic techniques, near-infrared Raman spectroscopy (NIRS) is particularly promising because of the wealth of molecular-specific information contained in its spectra

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    119 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    In-Vivo Raman Spectroscopy of Barrett's Esophagus
    Study Start Date :
    Oct 1, 2004
    Actual Primary Completion Date :
    May 1, 2007
    Actual Study Completion Date :
    Oct 1, 2007

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      18 Years to 85 Years
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      • Closed to further enrollment

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Mayo Clinic Rochester Minnesota United States 55905

      Sponsors and Collaborators

      • Mayo Clinic
      • National Institutes of Health (NIH)

      Investigators

      • Principal Investigator: Louis M Wongkeesong, MD, Mayo Clinic

      Study Documents (Full-Text)

      None provided.

      More Information

      Additional Information:

      Publications

      None provided.
      Responsible Party:
      Louis-Michel Wong Kee Song, Principal Investigator, Mayo Clinic
      ClinicalTrials.gov Identifier:
      NCT00588575
      Other Study ID Numbers:
      • 1999-04 00
      • DK67148
      • Raman
      First Posted:
      Jan 8, 2008
      Last Update Posted:
      Dec 11, 2019
      Last Verified:
      Sep 1, 2009
      Keywords provided by Louis-Michel Wong Kee Song, Principal Investigator, Mayo Clinic
      Barrett's Esophagus
      Additional relevant MeSH terms:
      Barrett Esophagus

      Study Results

      No Results Posted as of Dec 11, 2019