CBT for Anxiety Disorder in Children With Co-morbid ASD
Study Details
Study Description
Brief Summary
Children with Autism Spectrum Disorder (ASD) often have other difficulties as a result of the disorder. Up to half of the children with ASD are thought to suffer with anxiety in a way that interferes with their wellbeing and every day functioning. In this project the investigators will study the effect of the group program The Cool Kids Anxiety Program: Autism Spectrum Disorder Adaptation (Cool Kids ASD) - an anxiety treatment program specific developed for children with ASD. The investigators expect a decrease in the overall anxiety level together with an increase in the ability of handling anxiety.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The primary objective is to investigate the effect of a manualised Cognitive Behavioural Therapy (CBT) programme The Cool Kids Anxiety Program: Autism Spectrum Disorder Adaptation (Cool Kids ASD) for anxiety disorder adapted to children with Autism Spectrum Disorder (ASD) in a waitlist controlled design.
The investigators will investigate treatment effects on anxiety diagnosis and anxiety symptoms. Further, the investigators will investigate outcomes related to general functioning, co-morbid psychiatric disorders (Obsessive-Compulsive Disorder (OCD), hyperkinetic disorder and depression) and level of ASD symptoms (social and communicative skills).
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: CBT
|
Behavioral: CBT
The group based manualised CBT intervention consists of The Cool Kids Anxiety Program: Autism Spectrum Disorder Adaptation (Cool Kids ASD).
Other Names:
|
| No Intervention: WL
|
Outcome Measures
Primary Outcome Measures
- Anxiety Disorders Interview Schedule for DSM-IV: Parent & Child interview schedule (ADIS/CP). [Change from baseline interview results at 14 weeks]
ADIS/CP is a structured interview involving both child and parents designed to assess for current episodes of anxiety disorders, and to permit differential diagnosis among the anxiety disorders according to DSM-IV criteria.
- Anxiety Disorders Interview Schedule for DSM-IV: Parent & Child interview schedule (ADIS/CP). [Change from baseline interview results at 3 months]
ADIS/CP is a structured interview involving both child and parents designed to assess for current episodes of anxiety disorders, and to permit differential diagnosis among the anxiety disorders according to DSM-IV criteria.
Secondary Outcome Measures
- Spence Children's Anxiety Scale (SCAS), [Change from baseline results at 14 weeks]
SCAS is a questionnaire for children and parents assessing the severity of anxiety symptoms broadly in line with the dimensions of anxiety disorder proposed by the DSM-IV. The scale assesses six domains of anxiety including generalized anxiety, panic/agoraphobia, social phobia, separation anxiety, obsessive-compulsive disorder and physical injury fears.
- Spence Children's Anxiety Scale (SCAS), [Change from baseline results at 3 months]
SCAS is a questionnaire for children and parents assessing the severity of anxiety symptoms broadly in line with the dimensions of anxiety disorder proposed by the DSM-IV. The scale assesses six domains of anxiety including generalized anxiety, panic/agoraphobia, social phobia, separation anxiety, obsessive-compulsive disorder and physical injury fears.
- Children's Anxiety Life Inference Scale (CALIS) [Change from baseline results at 14 weeks]
CALIS is designed to assess life interference attributed to fears and worries from child and parent perspectives. The measure targets interference on the child's life and on the parent's/family's life.
- Children's Anxiety Life Inference Scale (CALIS) [Change from baseline results at 3 months]
CALIS is designed to assess life interference attributed to fears and worries from child and parent perspectives. The measure targets interference on the child's life and on the parent's/family's life.
- Children's Automatic Thoughts Scale (CATS). [Change from baseline results at 14 weeks]
CATS is a developmentally sensitive, general measure of negative self-statements across both internalizing and externalizing problems. Four separate subscales of cognitive content are assessed including physical threat, social threat, personal failure, and hostility.
- Children's Automatic Thoughts Scale (CATS). [Change from baseline results at 3 months]
CATS is a developmentally sensitive, general measure of negative self-statements across both internalizing and externalizing problems. Four separate subscales of cognitive content are assessed including physical threat, social threat, personal failure, and hostility.
Other Outcome Measures
- Attention Deficit/Hyperactive Disorder-Rating Scale (ADHD-RS) [Change from baseline results at 14 weeks]
- Attention Deficit/Hyperactive Disorder-Rating Scale (ADHD-RS) [Change from baseline results at 3 months]
- Social Responsiveness Scale (SRS) [Change from baseline results at 14 weeks]
- Social Responsiveness Scale (SRS) [Change from baseline results at 3 months]
- Strength and Difficulties Questionnaire (SDQ) [Change from baseline results at 14 weeks]
- Strength and Difficulties Questionnaire (SDQ) [Change from baseline results at 3 months]
- The WHO-five Well-being Index (WHO-5) [Change from baseline results at 14 weeks]
- The WHO-five Well-being Index (WHO-5) [Change from baseline results at 3 months]
- Adaptive Behaviour Assessment System, Second Edition (ABAS-II) [Change from baseline results at 14 weeks]
- Adaptive Behaviour Assessment System, Second Edition (ABAS-II) [Change from baseline results at 3 months]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
ASD
-
Anxiety (not necessary diagnosed)
Exclusion Criteria:
-
IQ under 70
-
Not meeting diagnostic criteria for primary anxiety diagnosis on ADIS
-
Active psychosis
-
Untreated ADHD
-
Families not able to follow program
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Centre for Child and Adolescent Psychiatry | Risskov | Region Of Midtjylland | Denmark | 8240 |
Sponsors and Collaborators
- University of Aarhus
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2016-2018