RDW to Platlet Count Ratio in CKD Patients

Sponsor

Sohag University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05754827

Collaborator

(none)

100

Enrollment

12.9

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The aim of the study is to determine Red blood cell distribution width to platelet count ratio as a predictor of cardiovascular complications in CKD patients

Condition or Disease	Intervention/Treatment	Phase
Cardiovascular Complication	Diagnostic Test: RDW to platlet count ratio

Detailed Description

comparative study between RDW to Platlet count ratio in CKD patients without cardiovascular complications and CKD patients with cardiovascular complications

Study Design

Study Type:

Observational

Anticipated Enrollment :

100 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Red Blood Cell Distribution Width to Platelet Count Ratio as a Predictor of Cardiovascular Complications in CKD Patients

Anticipated Study Start Date :

Feb 22, 2023

Anticipated Primary Completion Date :

Feb 22, 2024

Anticipated Study Completion Date :

Mar 22, 2024

Arms and Interventions

Arm	Intervention/Treatment
1-CKD patients without cardiovascular complications	Diagnostic Test: RDW to platlet count ratio RDW to platlet ratio will be measured for all patients and results will be compared between groups
2-CKD patients with cardiovascular complications	Diagnostic Test: RDW to platlet count ratio RDW to platlet ratio will be measured for all patients and results will be compared between groups

Arm

Intervention/Treatment

1-CKD patients without cardiovascular complications

Diagnostic Test: RDW to platlet count ratio

RDW to platlet ratio will be measured for all patients and results will be compared between groups

2-CKD patients with cardiovascular complications

Diagnostic Test: RDW to platlet count ratio

RDW to platlet ratio will be measured for all patients and results will be compared between groups

Outcome Measures

Primary Outcome Measures

Comparison of results of RDW to platlet ratio in CKD patients [1 year]
Calculate RDW to platlet ratio for CKD patints with or without cardiovascular complications and compare the results

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:
CKD Patients and patients receive dialysis >18 years old
Exclusion Criteria:
Serious complications of any other organs
patients who had previously undergone kidney transplantation .
CKD patients with history of previous CVD
patients with an infection, blood transfusion or receiving immunosuppressive drugs, as this may have affected the inflammatory response within the 3 months
patients who were pregnant
patients with chronic hematological disease
patient<18 years

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Sohag University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Jankowski J, Floege J, Fliser D, Bohm M, Marx N. Cardiovascular Disease in Chronic Kidney Disease: Pathophysiological Insights and Therapeutic Options. Circulation. 2021 Mar 16;143(11):1157-1172. doi: 10.1161/CIRCULATIONAHA.120.050686. Epub 2021 Mar 15.

Responsible Party:

Doha Aly Mohamed, Dr, Sohag University

ClinicalTrials.gov Identifier:

NCT05754827

Other Study ID Numbers:

CKD and CV complications

First Posted:

Mar 6, 2023

Last Update Posted:

Mar 6, 2023

Last Verified:

Mar 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Study Results

No Results Posted as of Mar 6, 2023