Real-life Study of the Characteristics of Patients Treated With Ilaris® (Canakinumab) for Gouty Arthritis in France
Study Details
Study Description
Brief Summary
This was a non-interventional, retrospective, cross-sectional, descriptive study, conducted on the National Health Data System (Système National des Données de Santé, SNDS).
The study did not modify the doctor-patient relationship, nor the management or follow-up of patients. Patients with dispensation of canakinumab for gouty arthritis were selected over the period from 08 April 2018 to 07 April 2020; index date was defined as date of the first dispensation of canakinumab in community pharmacy during study period.
Patients were described at index date. Medical history and comorbidities, and previous treatments for gouty arthritis were assessed during 3 years prior to index date. Co-treatments of interest for which standard treatments for gouty arthritis were contraindicated or required precautions for use were assessed during 6 months prior to index date.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Outcome Measures
Primary Outcome Measures
- Number of patients treated with canakinumab in France for the treatment of gouty arthritis [2 years]
Secondary Outcome Measures
- Mean age of patients [3 years]
- Number of male patients [3 years]
- Geographic location of patients [3 years]
- Number of patients with previous treatments for gouty arthritis [3 years]
- Medical history of patients [3 years]
- Number of patients with comorbidities [3 years]
Eligibility Criteria
Criteria
Inclusion Criteria:
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Received at least one reimbursement of Ilaris® from 08 April 2018 to 07 April 2020.
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Benefited from at least one of the following healthcare consumptions during 3 years prior to index date:
o At least one hospitalization with a main diagnosis or a related diagnosis in a Medical Unit Summary or a significant associated diagnosis in a Standardized Discharge Summary corresponding to the International Classification of Diseases, 10th Revision (ICD-10) code:
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M10.0 "Idiopathic gout"
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M10.1 "Saturnine gout"
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M10.2 "Medicated gout"
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M10.3 "Gout due to impaired renal function"
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M10.4 "Other secondary gout"
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M10.9 "Gout, unspecified"
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And/or an active long-term disease (Affection Longue Durée, ALD) with an ICD-10 code: "M10 Gout"
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And/or at least one dispensation of colchicine and urate-lowering therapy (allopurinol and/or febuxostat and/or benzbromarone and/or probenecid) at any time.
Exclusion Criteria:
None
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Novartis | Paris | France | 92506 |
Sponsors and Collaborators
- Novartis Pharmaceuticals
Investigators
- Study Director: Novartis Pharmaceuticals, Novartis Pharmaceuticals
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CACZ885HFR01