Red Cell Distribution Width and Mortality in Adult Pneumonia Patients

Sponsor
Rambam Health Care Campus (Other)
Overall Status
Unknown status
CT.gov ID
NCT01271205
Collaborator
(none)
2,000

Study Details

Study Description

Brief Summary

Abstract Pneumonia is a leading cause of severe morbidity and mortality among adults. During the last two decades, several scores were developed to evaluate the probability of morbidity and mortality among patients with community acquired pneumonia (CAP), such as the PORT score and the CURB65. Recently, several studies showed that elevated Red Cell Distribution Width (RDW) could be used as a prognostic tool for predicting severe morbidity and mortality among patients with cardiac diseases.

RDW is a quantitative measure for red blood cell (RBC) size variability. Recent studies have suggested that high levels of RDW are in association with higher mortality among cardiovascular patients.

RDW has not yet been studied as a prognostic sign in CAP. The goal of this study is to examine the role of RDW as a prognostic factor for severe morbidity and mortality among patients who were hospitalized with CAP , independently to Hemoglobin levels, renal function and inflammatory markers.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    2000 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Retrospective
    Study Start Date :
    Jan 1, 2011

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      18 Years and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:

      patients 18 years and older, hospitalized due to pneumonia between 2005-2010. All patients must have RDW values.

      -

      Exclusion Criteria:
      • under 18 no RDW value The primary cause of hospitalization was not pneumonia

      Contacts and Locations

      Locations

      No locations specified.

      Sponsors and Collaborators

      • Rambam Health Care Campus

      Investigators

      None specified.

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT01271205
      Other Study ID Numbers:
      • 580CTIL
      First Posted:
      Jan 6, 2011
      Last Update Posted:
      Jan 6, 2011
      Last Verified:
      Dec 1, 2010
      Keywords provided by , ,
      Additional relevant MeSH terms:

      Study Results

      No Results Posted as of Jan 6, 2011