Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient

Sponsor

Sohag University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05595278

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

3.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Condition or Disease	Intervention/Treatment	Phase
Myocardial Infarction	Diagnostic Test: (CBC) ,(NT-proBNP) ,(cTnT)

Detailed Description

Patients and methods:

Type of study: Observational prospective study
Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.
Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.
Study Methods:
A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.
All patients included in the study will be subjected to:

Full history:
Personal history: e.g. age, sex and smoking.
Family history of cardiac diseases
Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history
Detailed clinical examination
Electrocardiogram
Laboratory investigation:
Routine investigation in the form of CBC including RDW
Specific investigation which include NT-proBNP and cTnT

Study Design

Study Type:

Observational

Anticipated Enrollment :

30 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Detrmination of the Relationship Between Red Cell Distribution Width ,NT-proBNP and cTnT in Acute Myocardial Infraction Patients

Anticipated Study Start Date :

Nov 13, 2022

Anticipated Primary Completion Date :

Jun 13, 2023

Anticipated Study Completion Date :

Jul 13, 2023

Outcome Measures

Primary Outcome Measures

(CBC) [6 months]
measurement of CBC will be performed at the time of admission and by the time of discharge.
(NT-proBNP [6 months]
measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge.
(cTnT) [6 months]
measurement of cTnT levels will be performed at the time of admission and by the time of discharge

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

patients diagnosed as acute myocardial infarction and admitted to department of cardiology and cardiac care unit at Sohag cardiology and gastroenterology center according to inclusion and exclution criteria

Exclusion Criteria:

Patient with:

Decompensated heart failure
Pulmonary hypertention
Acute pulmonary embolism
Septic shock

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Sohag University Hospital	Sohag		Egypt

Sponsors and Collaborators

Sohag University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:

Hemat Kamel Maarouf, Resident doctor at clinical and chemical pathology department, Sohag University

ClinicalTrials.gov Identifier:

NCT05595278

Other Study ID Numbers:

Soh-Med-2210-05

First Posted:

Oct 26, 2022

Last Update Posted:

Nov 15, 2022

Last Verified:

Nov 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Myocardial Infarction

Infarction

Study Results

No Results Posted as of Nov 15, 2022