HA-AKI: Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes

Sponsor

Centre Hospitalier Universitaire Vaudois (Other)

Overall Status

Completed

CT.gov ID

NCT01151514

Collaborator

(none)

Location

Study Details

Study Description

Brief Summary

Few studies analyzed the referral time to nephrologists and its impact on the patient outcome in a large cohort. The investigators described the incidence and determined the outcome with respect to renal function recovery, renal replacement therapy (RRT) requirement and in-hospital mortality of Hospital Acquired Acute Kidney Injury (HA-AKI) without nephrology referral (nrHA-AKI) and late referred HA-AKI patients to nephrologists (lrHA-AKI) compared with early referral patients (erHA-AKI). The patients included were admitted to the tertiary care academic center of Lausanne (Switzerland) between 2004 and 2008, in the medical and surgical services and in the intensive care unit (ICU).

Condition or Disease	Intervention/Treatment	Phase
Renal Replacement Therapy Mortality	Other: Nephrologist referral

Study Design

Study Type:

Observational

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes

Arms and Interventions

Arm	Intervention/Treatment
nrHA-AKI patients Patients with hospital-acquired acute kidney injury not referred to the nephrologists	Other: Nephrologist referral Nephrologist specialty, renal replacement therapy Other Names: Control group: early-referred patients with HA-AKI.
lrHA-AKI patients Patients with hospital-acquired acute kidney injury whao are late referred to the nephrologists	Other: Nephrologist referral Nephrologist specialty, renal replacement therapy Other Names: Control group: early-referred patients with HA-AKI.

Arm

Intervention/Treatment

nrHA-AKI patients

Patients with hospital-acquired acute kidney injury not referred to the nephrologists

Other: Nephrologist referral

Nephrologist specialty, renal replacement therapy

Other Names:

Control group: early-referred patients with HA-AKI.

lrHA-AKI patients

Patients with hospital-acquired acute kidney injury whao are late referred to the nephrologists

Other: Nephrologist referral

Nephrologist specialty, renal replacement therapy

Other Names:

Control group: early-referred patients with HA-AKI.

Outcome Measures

Primary Outcome Measures

Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes []
Recovery of renal function during hospital stay. Requirement for renal replacement therapy.

Secondary Outcome Measures

Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes []
Length of hospital stay. In-hospital mortality.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 90 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Adult patients.
Hospitalization in the medicine and surgery wards and in the intensive care unit.
Hospitalized patients with acquired acute kidney injury according to the
Acute Kidney Injury Network (AKIN)criteria.
HA-AKI patients with no referral to the nephrologist (nrHA-AKI).
HA-AKI patients referred late (more than five days [> 5 days]) to the nephrologist (lrHA-AKI).
HA-AKI patients early referred (within five days after sCr increase) to the nephrologist (erHA-AKI).