WBV-IRM: The Reflex Mechanism Underlying Neuromuscular Effects Of The Whole Body Vibration

Sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT04516798

Collaborator

(none)

Enrollment

Location

Arm

Actual Duration (Days)

121.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study was conducted to determine whether the spinal reflex mechanism underlying the neuromuscular effects of whole body vibration (WBV) is tonic vibration reflex. Local and whole body vibration reflex latencies were measured in young adult healthy volunteers.

Condition or Disease	Intervention/Treatment	Phase
Reflex, Ankle, Decreased	Other: vibration	N/A

Detailed Description

A total of eight volunteers were included according to the inclusion and exclusion criteria. The subjects were vibrated while standing upright with the WBV device (PowerPlate® Pro5). The 30, 35 and 40 Hz WBVs were applied for thirty seconds for each frequency with an amplitude of 2 mm. In the same session, 100, 135 and 150 Hz local vibrations were applied to the right Achilles tendon for thirty seconds for each frequency. 100, 135 and 150 Hz local vibrations were then applied to the right heel for thirty seconds for each frequency with an interval of five seconds. Vibration stimuli were recorded accelerometers. Reflex muscle responses were recorded from the right soleus muscle at a sampling rate of 40 KHz. Recording electrodes were placed on the belly of the right soleus muscle and the ground electrode was placed on the right medial malleolus.

The data were recorded with the PowerLab device, the records were processed and analyzed offline from the LabChart program. After the EMG records are filtered and rectified, reflex latencies were measured by cumulative averaging method using the accelerometer records as triggers (Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Türker KS.A new method to determine reflex latency induced by high rate stimulation of the nervous system.Front Hum Neurosci.2014 Jul 18; 8: 536.doi: 10.3389 / fnhum.2014.00536). After determining the Achilles tendon vibration reflex latency and the reflex latency induced by WBV, it was compared with statistical methods.

Study Design

Study Type:

Interventional

Actual Enrollment :

8 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Intervention Model Description:

Self controlled experimental studySelf controlled experimental study

Masking:

None (Open Label)

Primary Purpose:

Basic Science

Official Title:

The Reflex Mechanism Underlying The Neuromuscular Effects Of The Whole Body Vibration

Actual Study Start Date :

Oct 5, 2020

Actual Primary Completion Date :

Oct 7, 2020

Actual Study Completion Date :

Oct 7, 2020

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Experiment Local and whole body vibration were applied	Other: vibration local and whole-body vibration were applied

Arm

Intervention/Treatment

Experimental: Experiment

Local and whole body vibration were applied

Other: vibration

local and whole-body vibration were applied

Outcome Measures

Primary Outcome Measures

reflex latency [during intervention, an average of 8 minutes]
The time between the vibration stimulus and the reflex muscle response triggered by it was defined as the latency.

Eligibility Criteria

Criteria

Ages Eligible for Study:

20 Years to 40 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Healthy
Young adult (20-40 years old)
Both gender
Volunteer

Exclusion Criteria:

Cardiac disorder (Rhythm / conduction disorder, Cardiac pacemaker, Ischemic heart disease)
Finding or suspected active deep vein thrombosis,
History of deep vein thrombosis and pulmonary embolism,
Orthostatic hypotension
Hypertension
Presence of fracture in the lower limb
Achilles Contractures
Active inflammatory, rheumatological or infectious disease in the lower limb
Peripheral nerve lesions such as polyneuropathy, radiculopathy in the lower limb
Those with a history of Achilles tendinopathy / bursitis
Those with a history of kidney stones
Patients with dizziness and balance problems,
Cases with lesions on the skin surface where electrodes were attached
Those with communication-cooperation problems
Having a history of panic attacks

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Istanbul Physical Medicine Rehabilitation Training & Research Hospital	İstanbul		Turkey	34173

Sponsors and Collaborators

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Investigators

Principal Investigator: Ilhan Karacan, Assoc Prof, Istanbul Physical Medicine Rehabilitation Training & Research Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

ClinicalTrials.gov Identifier:

NCT04516798

Other Study ID Numbers:

ISTANBULPMR

First Posted:

Aug 18, 2020

Last Update Posted:

Oct 27, 2020

Last Verified:

Oct 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Istanbul Physical Medicine Rehabilitation Training and Research Hospital

whole body vibration

tonic vibration reflex

muscle spindle

Additional relevant MeSH terms:

Reflex, Abnormal

Study Results

No Results Posted as of Oct 27, 2020