GLP-2 (Glucagonlike Peptide-2) and Blood Flow
Sponsor
Glostrup University Hospital, Copenhagen (Other)
Overall Status
Completed
CT.gov ID
NCT00540215
Collaborator
(none)
15
1
2
4
3.7
Study Details
Study Description
Brief Summary
It is the study aim to investigate the effect of glp-2 on blood flow in humans. we wish to study eventual changes in renal blood flow, carotic blood flow and cardiac out put.
GLP-2 will be administered subcutaneously, and the effect monitored by doppler ultra sound scannings and cotinuesly measuring of cardiac out put and blood pressure.
The study will include 15 healhty volunteers, 10 wil receive 450 nmol GLP-2 and 5 will receive 1 ml of isotonic saline (as baseline reference).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
se the above
Study Design
Study Type:
Interventional
Actual Enrollment
:
15 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
Single (Participant)
Primary Purpose:
Basic Science
Official Title:
The Role of GLP-2 in Univercal Changes in Blood Flow in Humans
Study Start Date
:
Oct 1, 2007
Actual Primary Completion Date
:
Jan 1, 2008
Actual Study Completion Date
:
Feb 1, 2008
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: 1 450 nmol GLP-2 SC |
Other: Glucagonlike peptide
450 nmol native form, synthetic
|
| Placebo Comparator: 2 1 ml isotonic saline SC |
Other: Glucagonlike peptide
450 nmol native form, synthetic
|
Outcome Measures
Primary Outcome Measures
- effect of glp-2 [during study]
Secondary Outcome Measures
- potential new ideas for further studies [months to years]
Eligibility Criteria
Criteria
Ages Eligible for Study:
20 Years
to 60 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Age 20-60
-
Healthy
-
No medication
-
Not pregnant
Exclusion Criteria:
- All of the persons not meeting the abowe mentioned criteria
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Glostrup University Hospital | Glostrup | Region Hovedstaden | Denmark | 2600 |
Sponsors and Collaborators
- Glostrup University Hospital, Copenhagen
Investigators
- Principal Investigator: lasse bremholm, MD, Glostrup university hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00540215
Other Study ID Numbers:
- H-D-2007-0050
First Posted:
Oct 5, 2007
Last Update Posted:
Feb 11, 2011
Last Verified:
Oct 1, 2007