Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

Sponsor
National Center for Research Resources (NCRR) (NIH)
Overall Status
Completed
CT.gov ID
NCT00004661
Collaborator
University of California, Los Angeles (Other)
20

Study Details

Study Description

Brief Summary

OBJECTIVES:

Determine the relationship between serum calcium concentrations and parathyroid hormone secretion in patients with pseudohypoparathyroidism.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    PROTOCOL OUTLINE:

    Patients are tested for parathyroid hormone response following sequential graded intravenous infusions of sodium citrate and calcium gluconate. Assays include ionized calcium and intact parathyroid hormone.

    Study Design

    Study Type:
    Observational
    Study Start Date :
    May 1, 1993

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      12 Years and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      PROTOCOL ENTRY CRITERIA:

      --Disease Characteristics-- Pseudohypoparathyroidism, i.e.: Renal resistance to parathyroid hormone OR Albright hereditary osteodystrophy No other illness unless related to pseudohypoparathyroidism No pregnant women

      Contacts and Locations

      Locations

      No locations specified.

      Sponsors and Collaborators

      • National Center for Research Resources (NCRR)
      • University of California, Los Angeles

      Investigators

      • Study Chair: Mitchell E. Geffner, University of California, Los Angeles

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00004661
      Other Study ID Numbers:
      • 199/11909
      • UCLA-541
      First Posted:
      Feb 25, 2000
      Last Update Posted:
      Jun 24, 2005
      Last Verified:
      Dec 1, 2001

      Study Results

      No Results Posted as of Jun 24, 2005