Relationship of Addictions to Obesity, Physical Activity and Vascular Ageing in Young Adults
Study Details
Study Description
Brief Summary
This is a cross-sectional observational study whose objective is to analyse the relationship between behavioural addictions and drug addictions with obesity, physical activity, sedentary lifestyle, arterial stiffness and vascular ageing in young adults, since many of the lifestyles of adulthood are established early in life, and it is easier to prevent them before they start than to achieve their abandonment once they are established as unhealthy lifestyles
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Behavioural addictions. Brief Questionnaire of Pathological Gambling (CBJP), Lie/Bet scale, Compulsive Internet Use Scale (CIUS), Smartphone Dependence and Addiction Scale (EDAS-18), Questionnaire of Experiences Related to Video Games (CERV). Drug addictions: Alcohol, Smoking and Substance Involvement Screening Test (ASSIST V3.0), Drug Abuse Screening Test (DAST-20), Alcohol Use Disorders Identification Test (AUDIT) and Fagerström test. Obesity and body composition: Weight, height, waist circumference, hip circumference and Inbody 230®. Diet: Mediterranean Diet Adherence Questionnaire. Physical activity: International Physical Activity Questionnaire (IPAQ), Actigraph GTX3 accelerometer and Marshall questionnaire. Analysis of vascular structure and function and target organ lesions. Pulse wave analysis (PWA) and femoral carotid pulse wave velocity (VOPcf) (Sphygmocor System). Cardio Ankle Vascular Index (CAVI), ankle-ankle pulse wave (VOPbt) and ankle-ankle index (ABI) (Vasera VS-2000®). Retinal vascular injury (TOPCON TRC NW 200). Cardiac lesion (General electric 5000). Kidney Injury: analytical variables. Brain Injury: Montreal Cognitive Assessment (MoCA). Vascular ageing (VOPcf and VOPbt). Other variables. Basal glycaemia, HbA1c. TSH, lipid profile, creatinine and creatinine albumin index and Vit D. Measurement of blood pressure and drug consumption.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Young people with addiction Both behavioural and drug addiction will be assessed. Participants with scores consistent with an addiction will be included in this group. |
|
| Young people without addiction Both behavioural and drug addiction will be assessed. Participants with scores not consistent with an addiction will be included in this group. |
Outcome Measures
Primary Outcome Measures
- Pulse wave velocity [1 year]
Measurement by SphygmoCor (meters/seg)
Secondary Outcome Measures
- Cardio Ankle Vascular Index (CAVI) [1 year]
It will be determined using the Vasera VS-2000® device (not units)
- Pathological gambling [1 year]
Brief Questionnaire on Pathological Gambling (CBJP), with 4 dichotomous items (yes/no) referring to gambling habits, feelings of guilt, inability to give up gambling and use of household money for gambling. It is considered pathological from 2 points onwards. Also, Lie/Bet scale will also be used. It consists of two items, one of them referring to lying and the other to gambling, and will be considered problematic if both items are answered positively.
- Internet use [1 year]
Compulsive Internet Use Scale (CIUS). It consists of 14 questions with a 5-point Likert scale for the answer. The cut-off point is 28.
- Compulsive use of mobile phones [1 year]
Smartphone Dependence and Addiction Scale (EDAS-18). It consists of 18 questions with a 5-point Likert scale for the answer. Average scores: No dependence: ≤ 2.23; dependence: between 2.24 and 3.5; addiction: ≥ 3,6
- Videogames use [1 year]
Video Game Related Experiences Questionnaire (VREQ), with two dimensions: negative consequences and avoidance. It consists of 17 questions with a 4-point Likert scale for the answer. The cut-off point is 26 points.
- Use or abuse of alcohol, tobacco and illegal drugs [1 year]
Alcohol, Smoking and Substance Involvement Screening Test (ASSIST V3.0), with 8 items in relation to the consumption of 9 substances, categorised into three risk levels: low (0-3 points), moderate (4-26 points) and high (more than 27 points).
- Problem drug use [1 year]
Drug Abuse Screening Test (DAST-20), 20 questions with dichotomous answers (Yes/No) and a cut-off point of 5
- Excessive alcohol consumption [1 year]
Alcohol Use Disorders Identification Test (AUDIT), with 10 questions, allows to identify: risky use (8-15 points), harmful use (16-19 points) and dependence (more than 20 points)
- Nicotine dependence [1 year]
Fagerström test. With six questions it classifies into mild (less than 4 points), moderate (4-6 points) or severe dependence (more than 7 points).
- Waist and hip circumference [1 year]
The waist and hip circumference shall be measured with a tape measure (cm).
- Body composition [1 year]
The analysis of body composition shall be carried out with the impedance-meter Inbody 230® (kg).
- International Physical Activity Questionnaire (IPAQ) [1 year]
Physical activity measurement using the International Physical Activity Questionnaire (IPAQ) (min/day)
- Accelerometer [1 year]
Physical activity measurement using actigraph GTX3 accelerometer for 7 days (counts)
- Adherence to the Mediterranean diet [1 year]
Diet will be assessed with the Mediterranean Diet (MD) adherence questionnaire, developed in the PREDIMED project and consisting of 14 items with dichotomous responses.(points)
- Sleep quality and quantity [1 year]
Pittsburgh Sleep Quality Index (PSQI) which assesses the quality of sleep disturbance in the last month. It is composed of 19 items. The cut-off point for poor sleep quality is 5 points or higher. (points)
- Sleep disruption [1 year]
The Ford Insomnia Response to Stress Test, which assesses the likelihood of sleep disruption (points)
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients between 18 and 34 years of age who agree to participate in the study and do not meet any exclusion criteria.
Exclusion Criteria:
- Subjects who are terminally ill, who are unable to travel to health centres for the corresponding examinations, and who do not sign informed consent.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Primary Care Research Unit of Salamanca | Salamanca | Spain | 37005 |
Sponsors and Collaborators
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
- Castilla-León Health Service
- Instituto de Investigación Biomédica de Salamanca
Investigators
- Principal Investigator: Manuel A Gomez-Marcos, Dr, Primary Care Research Unit
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- GRS 2500/B/22
- IBYE22/00003