The Relationship Between Breastfeeding During Early Pregnancy and Miscarriage

Sponsor
Siirt University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05461963
Collaborator
(none)
76
1
6.1
12.4

Study Details

Study Description

Brief Summary

Breastfeeding provides various health and psychological benefits to mothers and their babies. It also acts as an effective method of natural contraception when applied strictly for up to six months after birth. Studies show that breastfeeding times are getting longer in the USA and more babies are breastfed for more than 12 months compared to the past. Recent research shows that 57% of US infants are breastfed until at least six months of age, and more than a third continue to be breastfed for up to 12 months. Prolonged breastfeeding durations increase the prevalence of breastfeeding during pregnancy, especially with the shortening of the intervals between pregnancies. Breastfeeding during pregnancy is a relatively common practice in many parts of the world. According to the data of studies conducted in low- and middle-income countries, it has been determined that 35% of the last born babies continue to be breastfed in the next pregnancy of their mothers. It has also been shown that the prevalence of breastfeeding during pregnancy in low-income countries is between 15% and 50%. Few research has been done on the relationship between breastfeeding during pregnancy and maternal, infant, or pregnancy outcomes. Some studies have suggested that hormonal mechanisms in pregnancy may link breastfeeding during pregnancy and abortion. When babies stimulate the nipple and areola during sucking, they trigger the release of oxytocin in the mother, causing a series of reactions that push the milk towards the nipple. We know that the prevalence of short and long breastfeeding intervals in pregnancy is high in our country. Therefore, in this study, we are planning to investigate whether there is a relationship between breastfeeding during pregnancy and miscarriage based on this information.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Our aim in this study is to investigate whether breastfeeding during pregnancy increases the risk of abortion and to determine whether there is a relationship between them. For this purpose, approximately 76 pregnant women who were pregnant and continuing to breastfeed in Siirt Training and Research Hospital between June 2022 and December 2022 will be included in the study. The same number (n:76) non-breastfeeding pregnant control group will be included in the study. Age, gestational week, pregnancy history (gravida, parity, abortion, missed, ectopic),breastfeeding time in previous pregnancies, bleeding, daily breastfeeding frequency and medical history of the pregnant will be recorded. In the light of the information obtained in this way, we plan to determine whether there is a relationship between breastfeeding during pregnancy and abortion.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    76 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    Breastfeeding and Miscarriage Relationship
    Actual Study Start Date :
    Jun 26, 2022
    Anticipated Primary Completion Date :
    Dec 30, 2022
    Anticipated Study Completion Date :
    Dec 30, 2022

    Arms and Interventions

    Arm Intervention/Treatment
    breastfeeding pregnants( n:76)

    pregnants in early weeks of pregnancy who practice breastfeeding

    control group ( n:76)

    pregnants in early weeks of pregnancy who not practice breastfeeding

    Outcome Measures

    Primary Outcome Measures

    1. Miscarriage, ratio in breastfeeding pregnant women [From the 6th week of pregnancy to the 20th week.]

      Miscarriage is the spontaneous loss of a pregnancy before the 20th week,

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    Female
    Inclusion Criteria:
    • being breastfeeding

    • being at the 1.st trimester of pregnancy

    Exclusion Criteria:
    • history of inherited thrombophilia

    • history of uterine anomaly

    • history of trauma

    • history of genetic anomaly

    • history of habitual abortus

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Siirt Üniversity Medical Faculty Siirt Turkey 56000

    Sponsors and Collaborators

    • Siirt University

    Investigators

    • Study Director: Şerif Aksin, Siirt University Medical Faculty Obstetrics and Gynecology Departmant

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Serif Aksin, associate professor, Siirt University
    ClinicalTrials.gov Identifier:
    NCT05461963
    Other Study ID Numbers:
    • SiirtUN
    First Posted:
    Jul 18, 2022
    Last Update Posted:
    Jul 18, 2022
    Last Verified:
    Jul 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Jul 18, 2022