Evaluation of the Relationship Between Dental Caries and Growth Parameters in Preschool Children
Study Details
Study Description
Brief Summary
Untreated dental caries are very common in preschool children. Pain and inflammation due to dental caries have been reported to affect eating and sleeping disorders, affecting growth and development. The aim of this study was to compare the changes in serum IGF-1 and IGFBP-3 levels, height and weight gain before and after treatment in patients with dental caries-related inflammation and pain in preschool children and to compare these children with children without dental caries. Thirty children aged between 3-6 years with dental caries with pulp were identified using ICDAS II and dmft index as the study group.30 children dental caries including pulp, will be included using the same indices as the control group. In the study group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined before and at the 6th month after treatment. In the control group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined at the 6th month following the first dental examination. IGF-1, IGFBP-3 and anthropometric measurements will be compared between first dental examination and 6th month values in the study and control groups, and between first dental examination and 6th month time points between the groups.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
In addition to growth parameters, the Children's Sleeping Habits Questionnaire and the Early Childhood Oral Health Impact Scale will be compared before the 6th month of dental treatment and compared
Study Design
Outcome Measures
Primary Outcome Measures
- Growth parameters [before dental treatment]
In the study group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined before and at the 6th month after treatment. In the control group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined at the 6th month following the first dental examination. IGF-1, IGFBP-3 and anthropometric measurements will be compared between first dental examination and 6th month values in the study and control groups, and between first dental examination and 6th month time points between the groups.
- Growth parameters [6 months after dental treatment]
In the study group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined before and at the 6th month after treatment. In the control group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined at the 6th month following the first dental examination. IGF-1, IGFBP-3 and anthropometric measurements will be compared between first dental examination and 6th month values in the study and control groups, and between first dental examination and 6th month time points between the groups.
Secondary Outcome Measures
- Children's Sleep Habits Questionnaire [before dental treatment]
In the study group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment.In the control group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment
- Children's Sleep Habits Questionnaire [a week after dental treatment]
In the study group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment.In the control group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment
- Children's Sleep Habits Questionnaire [6 months after dental treatment]
In the study group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment.In the control group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment
- Early Childhood Oral Health Impact Scale [before dental treatment]
n the study Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment.In the control group Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment
- Early Childhood Oral Health Impact Scale [a week after dental treatment]
n the study Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment.In the control group Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment
- Early Childhood Oral Health Impact Scale [6 months after dental treatment]
n the study Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment.In the control group Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment
Eligibility Criteria
Criteria
Inclusion Criteria:
For study group
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(3-6 years) preschool children
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Children whose dental treatments are indicated under general anesthesia
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Children with primary dentition
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Children with early childhood caries (dmft index d≥ 3)
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Children with symptoms of pulpitis or periapical infection in at least one tooth
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Children with dental problems at least in the last 6 months
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Volunteering to participate in the study. For the control group,
1- (3-6 years) preschool children 2-Children with primary dentition 3- Children without pulpitis symptoms or periapical infection during dental examination 4-Volunteering to participate in the study.
Exclusion Criteria:
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Children who do not show adequate compliance during blood sampling
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Consent form is not signed
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Children with chronic and systemic diseases that may affect growth and development
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Children using anti-inflammatory
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Patients with physical and mental disabilities
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Patients using corticosteroids in the last 6 months
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If a child is diagnosed with any of the these diseases during the study
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Basak Gunay | Istanbul | Turkey |
Sponsors and Collaborators
- Bezmialem Vakif University
Investigators
- Principal Investigator: Basak Gunay, Bezmialem Vakif University
- Study Director: Mustafa Sarp Kaya, Bezmialem Vakif University
- Study Chair: Ilker Tolga Ozgen, Bezmialem Vakif University
Study Documents (Full-Text)
None provided.More Information
Publications
- Alkarimi HA, Watt RG, Pikhart H, Jawadi AH, Sheiham A, Tsakos G. Impact of treating dental caries on schoolchildren's anthropometric, dental, satisfaction and appetite outcomes: a randomized controlled trial. BMC Public Health. 2012 Aug 29;12:706. doi: 10.1186/1471-2458-12-706.
- Duijster D, Sheiham A, Hobdell MH, Itchon G, Monse B. Associations between oral health-related impacts and rate of weight gain after extraction of pulpally involved teeth in underweight preschool Filipino children. BMC Public Health. 2013 Jun 3;13:533. doi: 10.1186/1471-2458-13-533.
- Ersoy B, Yücetürk AV, Taneli F, Urk V, Uyanik BS. Changes in growth pattern, body composition and biochemical markers of growth after adenotonsillectomy in prepubertal children. Int J Pediatr Otorhinolaryngol. 2005 Sep;69(9):1175-81.
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