Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases

• Sponsor: The Dental Hospital of Zhejiang University School of Medicine (Other)
• Overall Status: Not yet recruiting
• CT.gov ID: NCT05403216
• Collaborator: (none)
• Enrollment: 60
• Anticipated Duration (Months): 30

Study Details

Study Description

Brief Summary

On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.

Condition or Disease	Intervention/Treatment	Phase
Oral Lichen Planus	Other: no intervention

Study Design

• Study Type: Observational
• Anticipated Enrollment: 60 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Clinical Value of the Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases
• Anticipated Study Start Date: Jul 1, 2022
• Anticipated Primary Completion Date: Dec 31, 2024
• Anticipated Study Completion Date: Dec 31, 2024

Arms and Interventions

Arm	Intervention/Treatment
OLP(-) Oral lichen planus (OLP) with negative thyroid antibody group
OLP(+) OLP with positive thyroid antibody group	Other: no intervention

Outcome Measures

Primary Outcome Measures

1. Oral lichen planus (OLP) lesions record [1 year]

   Record changes of lesions based on the symptoms and signs of the oral lichen planus patient.

2. Level of thyroid function and antibody [1 year]

   The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 65 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• OLP patients without systemic disease

Exclusion Criteria:

• OLP patients with severe periodontal disease

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• The Dental Hospital of Zhejiang University School of Medicine

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Qianming Chen, professor, The Dental Hospital of Zhejiang University School of Medicine
• ClinicalTrials.gov Identifier: NCT05403216
• Other Study ID Numbers: I20210609
• First Posted: Jun 3, 2022
• Last Update Posted: Jun 3, 2022
• Last Verified: May 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Lichen Planus, Oral; Lichen Planus; Thyroid Diseases

Study Results

No Results Posted as of Jun 3, 2022