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The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05903677
Collaborator
(none)
50
Enrollment
12
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.

Condition or Disease Intervention/Treatment Phase
  • Other: magnesium levels

Detailed Description

Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.

Study Design

Study Type:
Observational
Anticipated Enrollment :
50 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery
Anticipated Study Start Date :
Jul 1, 2023
Anticipated Primary Completion Date :
Jun 1, 2024
Anticipated Study Completion Date :
Jul 1, 2024

Arms and Interventions

Arm Intervention/Treatment
Adults undergoing cardiac surgery without preoperative renal affection

Detect the preoperative magnesium levels in adults undergoing cardiac surgery without preoperative renal affection and follow up if they developed postoperative acute kidney injury or not.

Other: magnesium levels
Detection of the relationship between cardiac surgery associated AKI and preoperative magnesium levels.
Other Names:
  • Serum creatinine and blood urea nitrogen (BUN)

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level [Baseline]

      Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery.

    2. Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level [basline]

      Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

    3. Post cardiac surgery normal kidney functions with low preoperative magnesium level [basline]

      Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Inclusion Criteria:

    1. patients more than or equal 18 yrs.

    2. patients undergoing cardiac surgery between July 2023 and July 2024

    Exclusion Criteria:

    1. patients with known Kidney disease.

    2. patients less than 18 yrs

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Assiut University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Mostafa Ahmed Kaleed Abdelhalim, Resident doctor, Assiut University
    ClinicalTrials.gov Identifier:
    NCT05903677
    Other Study ID Numbers:
    • Preoperative magnesium and AKI
    First Posted:
    Jun 15, 2023
    Last Update Posted:
    Jun 15, 2023
    Last Verified:
    Jun 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Acute Kidney Injury

    Study Results

    No Results Posted as of Jun 15, 2023