The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease

• Sponsor: Peking University First Hospital (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT03397550
• Collaborator: (none)
• Enrollment: 100
• Location: 1
• Anticipated Duration (Months): 10.4
• Patients Per Site Per Month: 9.6

Study Details

Study Description

Brief Summary

The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.

Condition or Disease	Intervention/Treatment	Phase
Renal Insufficiency, Chronic; Chronic Kidney Diseases	Other: salt restriction education

Study Design

• Study Type: Observational
• Anticipated Enrollment: 100 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease
• Anticipated Study Start Date: Jun 18, 2022
• Anticipated Primary Completion Date: Dec 1, 2022
• Anticipated Study Completion Date: May 1, 2023

Outcome Measures

Primary Outcome Measures

1. ratings of taste sensitivity assessed by the ISO method of investigating sensitivity of taste（ISO 3972:1991） [up to 12 weeks after intervention]

   Taste sensitivity is measured by five taste solutions（salty、sour、bitter、sweet、umami). Every taste solution contains 8 different concentration. Detection , recognition and difference thresholds will be measured .Their definitions are as bellow. Detection threshold：minimum value of sensory stimulus needed to give rise to a sensation. The sensation need not be identified. Recognition threshold：minimum value of a sensory stimulus permitting identification of the sensation perceived. Difference threshold：value of the smallest perceptible difference in the physical intensity of a stimulus.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 80 Years
• Sexes Eligible for Study: All

Inclusion Criteria:

• stage 3-5 CKD patients

• clinical stable

Exclusion Criteria:

• renal replacement therapy

• cancer

• systemic infection

• Alzheimer's disease

• acute cardiovascular events, active hepatitis

• all other study-obstructive conditions

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Peking University First Hospital	Beijing		China

Sponsors and Collaborators

• Peking University First Hospital

Investigators

• Study Director: Jie Dong, Peking Universiy First Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Dong Jie, Nephrology chief physician, Peking University First Hospital
• ClinicalTrials.gov Identifier: NCT03397550
• Other Study ID Numbers: pekingUFH-cn
• First Posted: Jan 12, 2018
• Last Update Posted: May 10, 2022
• Last Verified: May 1, 2022

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Dong Jie, Nephrology chief physician, Peking University First Hospital: taste threshold; salt restriction
• Additional relevant MeSH terms: Kidney Diseases; Renal Insufficiency, Chronic; Renal Insufficiency

Study Results

No Results Posted as of May 10, 2022