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Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

Sponsor
Hospital Nossa Senhora da Conceicao (Other)
Overall Status
Unknown status
CT.gov ID
NCT01455662
Collaborator
(none)
100
Enrollment
1
Location
23
Duration (Months)
4.4
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

    Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    100 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome
    Study Start Date :
    Jan 1, 2010
    Anticipated Primary Completion Date :
    Dec 1, 2011
    Anticipated Study Completion Date :
    Dec 1, 2011

    Arms and Interventions

    Arm Intervention/Treatment
    all patients after cardiac arrest

    Outcome Measures

    Primary Outcome Measures

    1. mortality [1 year]

    Secondary Outcome Measures

    1. correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance [6 hours]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 80 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace
    Exclusion Criteria:

    pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

    • patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest

    • less 18 years old

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Conceição Hospital Porto Alegre Rio Grande do Sul Brazil

    Sponsors and Collaborators

    • Hospital Nossa Senhora da Conceicao

    Investigators

    • Principal Investigator: Vanessa Oliveira, MD, Conceição Hospital
    • Principal Investigator: Diego F Riveiro, MD, Hospital Nossa Senhora da Conceição

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Vanessa Martins de oliveira, Principal Investigator, Hospital Nossa Senhora da Conceicao
    ClinicalTrials.gov Identifier:
    NCT01455662
    Other Study ID Numbers:
    • 10086
    First Posted:
    Oct 20, 2011
    Last Update Posted:
    Nov 3, 2011
    Last Verified:
    Nov 1, 2011
    Keywords provided by Vanessa Martins de oliveira, Principal Investigator, Hospital Nossa Senhora da Conceicao
    cardiac arrest
    Additional relevant MeSH terms:
    Heart Arrest

    Study Results

    No Results Posted as of Nov 3, 2011