Glucose in Dialysis Water in Non-diabetics

• Sponsor: Regional Hospital Holstebro (Other)
• Overall Status: Completed
• CT.gov ID: NCT00439023
• Collaborator: (none)
• Enrollment: 18
• Location: 1
• Duration (Months): 12
• Patients Per Site Per Month: 1.5

Study Details

Study Description

Brief Summary

The purposes are

1. to measure the effect of dialysis with glucose on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations of glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and

2. to analysis the relationship between changes in blood pressure on the one hand and changes in vasoactive hormones on the other

Condition or Disease	Intervention/Treatment	Phase
Renal Failure, Chronic	Procedure: dialysis with glucose in dialysis water	Phase 4

Detailed Description

Measurement of hormones and blood pressure during dialysis treatment.

Study Design

• Study Type: Interventional
• Actual Enrollment: 18 participants
• Allocation: Randomized
• Intervention Model: Crossover Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Effect of Glucose in Dialysis Water on Blood Pressure and Vasoactive Hormones in Dialysis Patients
• Study Start Date: May 1, 2006
• Actual Study Completion Date: May 1, 2007

Outcome Measures

Primary Outcome Measures

1. Effect of glucose in dialysis water on blood pressure, insulin and vasoactive hormones [one week]

Secondary Outcome Measures

1. Relationship between changes in blood pressure and changes in hormones during treatment [one week]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

1. Age > 18 years,

2. Both men and women,

3. Dialysis treatment for at least three months

Exclusion Criteria:

1. Heart failure,

2. Chronic liver disease,

3. Diabetes mellitus,

4. Malignant disease,

5. Nephrotic syndrome,

6. Lack of compliance, 7 Unwillingness to participate

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Holstebro Hospital	Holstebro		Denmark	7500

Sponsors and Collaborators

• Regional Hospital Holstebro

Investigators

• Study Chair: Erling B Pedersen, Professor, Regional Hospital Holstebro

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00439023
• Other Study ID Numbers: MED.RES.2007.01.EBP
• First Posted: Feb 22, 2007
• Last Update Posted: Sep 15, 2015
• Last Verified: Sep 1, 2007

• Keywords provided by , ,: Chronic renal failure, dialysis, hemodialysis,
• Additional relevant MeSH terms: Renal Insufficiency; Kidney Failure, Chronic

Study Results

No Results Posted as of Sep 15, 2015