Uremic Toxins in the ICU: Patients After Cardiac Surgery
Sponsor
University Hospital, Ghent (Other)
Overall Status
Unknown status
CT.gov ID
NCT00752804
Collaborator
(none)
12
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3
87
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Study Details
Study Description
Brief Summary
Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients after cardiac surgery.The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
12 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Study of the Kinetics of Uremic Toxins in the ICU Patients With Acute Renal Failure, in Order to Optimize the Dialysis Dose: Patients After Cardiac Surgery
Study Start Date
:
Sep 1, 2008
Anticipated Primary Completion Date
:
Dec 1, 2015
Anticipated Study Completion Date
:
Dec 1, 2015
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: 1 Dialysis during 4 hours |
Procedure: Dialysis during 4 hours
Blood and dialysate sampling
|
Active Comparator: 2 Dialysis during 6 hours |
Procedure: Dialysis during 6 hours
Blood and dialysate sampling
|
Active Comparator: 3 Dialysis during 8 hours |
Procedure: Dialysis during 8 hours
Blood and dialysate sampling
|
Outcome Measures
Primary Outcome Measures
- Toxin removal [During dialysis]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- ICU patients after cardiac surgery with acute renal failure
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | University Hospital Ghent | Ghent | Belgium | 9000 |
Sponsors and Collaborators
- University Hospital, Ghent
Investigators
- Principal Investigator: Raymond Vanholder, MD, PhD, University Hospital, Ghent
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.Responsible Party:
University Hospital, Ghent
ClinicalTrials.gov Identifier:
NCT00752804
Other Study ID Numbers:
- 2008/374
First Posted:
Sep 15, 2008
Last Update Posted:
Jun 3, 2015
Last Verified:
Jun 1, 2015
Keywords provided by University Hospital, Ghent
Additional relevant MeSH terms: