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Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Sponsor
University Hospital, Limoges (Other)
Overall Status
Completed
CT.gov ID
NCT00199628
Collaborator
(none)
100
Enrollment
1
Location
107
Actual Duration (Months)
0.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    100 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
    Actual Study Start Date :
    Sep 1, 2005
    Actual Primary Completion Date :
    Aug 1, 2013
    Actual Study Completion Date :
    Aug 1, 2014

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      Female
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      Mothers having a child suffering from:

      • Neonatal membranous glomerulonephritis

      • Unexplained neonatal tubular defect

      • Unexplained thrombotic microangiopathy

      • Neonatal hemochromatosis

      Exclusion Criteria:
      • Any cause explaining the child's disease

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Limoges University Hospital Limoges France 87042

      Sponsors and Collaborators

      • University Hospital, Limoges

      Investigators

      • Principal Investigator: Vincent Guigonis, MD, Department of Pediatrics, Limoges University Hospital

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      University Hospital, Limoges
      ClinicalTrials.gov Identifier:
      NCT00199628
      Other Study ID Numbers:
      • I05001
      First Posted:
      Sep 20, 2005
      Last Update Posted:
      Jan 15, 2019
      Last Verified:
      Sep 1, 2005
      Keywords provided by University Hospital, Limoges
      fetomaternal tissular alloimmunization
      Mothers having a child suffering from:
      neonatal membranous glomerulonephritis
      unexplained neonatal tubular defect
      unexplained thrombotic microangiopathy
      neonatal hemochromatosis
      Additional relevant MeSH terms:
      Glomerulonephritis
      Glomerulonephritis, Membranous
      Hemochromatosis
      Infant, Newborn, Diseases
      Hemosiderosis

      Study Results

      No Results Posted as of Jan 15, 2019