Autonomic Modulation Recovery After Acute Resistance Exercise

Sponsor

Universidade Estadual Paulista Júlio de Mesquita Filho (Other)

Overall Status

Completed

CT.gov ID

NCT04569617

Collaborator

(none)

Enrollment

Locations

Arms

41.7

Actual Duration (Months)

24.5

Patients Per Site

0.6

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

To analyze the autonomic behavior in recovery post-acute resistance exercise performed in different intensities and body segments.

Condition or Disease	Intervention/Treatment	Phase
Resistance Training	Other: Resistance Training - UL endurance protocol Other: Resistance Training - UL strength protocol Other: Resistance Training - LL endurance protocol Other: Resistance Training - LL strength protocol	N/A

Detailed Description

Resistance training (RT) is recommended to people with different health condition. RT is recognized as safe and effective method of increasing muscle strength, physical fitness, muscle mass, and overall cardiovascular health. The magnitude of the RT effects is associated with the structure of the training program. Understanding these aspects may provide guidance for the RT prescription while reducing potential risk of cardiovascular events associated with the recovery period after exercise. The objective of the study is to compare the acute responses of the Autonomic Nervous System post RT performed with different intensities (endurance and strength) in different body segments (UL and LL). Our hypothesis is that different intensities and body segments influence the acute responses of the ANS in the post RT recovery period.

Study Design

Study Type:

Interventional

Actual Enrollment :

49 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Intervention Model Description:

This study is a cross-over clinical trialThis study is a cross-over clinical trial

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Autonomic Modulation Recovery After Acute Resistance Exercise in Different Intensities and Body Segments

Actual Study Start Date :

Aug 1, 2011

Actual Primary Completion Date :

Nov 30, 2012

Actual Study Completion Date :

Jan 20, 2015

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: upper limb endurance protocol UL endurance protocol - elbow flexion	Other: Resistance Training - UL endurance protocol UL endurance protocol - 2 series of 20 repetitions, elbow flexion at 40% of the maximum test force of 1 maximum repetition, (recovery 1 minutes between sets).
Active Comparator: upper limb strength protocol UL strength protocol - elbow flexion	Other: Resistance Training - UL strength protocol UL strength protocol - 2 series of 8 repetitions, elbow flexion at 80% of the maximum test force of 1 maximum repetition, (recovery 1 minutes between sets).
Active Comparator: lower limb endurance protocol LL endurance protocol - knee extension	Other: Resistance Training - LL endurance protocol LL endurance protocol - 2 series of 20 repetitions, elbow flexion at 40% of the maximum test strength of 1 maximum repetition, (recovery 1 minutes between sets).
Active Comparator: lower limb strength protocol LL strength protocol - knee extension	Other: Resistance Training - LL strength protocol LL strength protocol - 2 series of 8 repetitions, knee extension at 80% of the maximum test force of 1 maximum repetition, (recovery 1 minutes between sets).

Outcome Measures

Primary Outcome Measures

Acute responses of the Autonomic Nervous System post Resistance Training of the time-domain indices of Heart Rate Variability [the moments before and immediately after Resistance Training, performed with different intensities (endurance and strength) and body segments (UL and LL).]
Understand the effect of acute responses of the time-domain indices of Heart Rate Variability, RMSSD, and SDNN, comparing the behavior of these indices of in rest periods and immediate recovery after effort. Besides, to analyze the changes observed when applying different training intensities (endurance protocol 40% 1RM, and strength protocol 80% 1 RM) and body segments (elbow flexion [UL] and knee extension [LL]). RMSSD: root mean square of the successive differences between the RR intervals in the record, divided by the number of RR intervals in a given time minus one RR interval SDNN: standard deviation of all normal RR intervals.
Acute responses of the Autonomic Nervous System post Resistance Training of the geometric indices of Heart Rate Variability [the moments before and immediately after Resistance Training, performed with different intensities (endurance and strength) and body segments (UL and LL).]
Understand the effect of acute responses of the geometric indices of Heart Rate Variability, SD1, SD2, comparing the behavior of these indices of in rest periods and immediate recovery after effort. Besides, to analyze the changes observed when applying different training intensities (endurance protocol 40% 1RM, and strength protocol 80% 1 RM) and body segments (elbow flexion [UL] and knee extension [LL]). SD1: standard deviation of diagonal points SD2: standard deviation from longitudinal points
Acute responses of the Autonomic Nervous System post Resistance Training of the frequency domain of Heart Rate Variability, [the moments before and immediately after Resistance Training, performed with different intensities (endurance and strength) and body segments (UL and LL).]
Understand the effect of acute responses of the frequency domain of Heart Rate Variability, LF anf HF, both calculated in absolute (ms2) and normalized units (nu), comparing the behavior of these indices of in rest periods and immediate recovery after effort. Besides, to analyze the changes observed when applying different training intensities (endurance protocol 40% 1RM, and strength protocol 80% 1 RM) and body segments (elbow flexion [UL] and knee extension [LL]). LF: spectral components of low frequency, 0.04 - 0.15Hz HF: spectral components of high frequency, 0.15 - 0.40 Hz

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 30 Years

Sexes Eligible for Study:

Male

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Graduate students,
Age between 18 to 30 years
Healthy men, the Physical Activity Readiness Questionnaire (PAR-Q) was used to determine safety and possible risk of exercising based on participants' health history, the according American College of Sports Medicine, 2010.
Trained men, the International Physical Activity Questionnaire (IPAQ) was used to determine participants' physical activity level.

Exclusion Criteria: Participants who did not attend all the RT protocols and those with HR record with error higher than 5% (ectopic beats) will be excluded.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Luiz Carlos Marques Vanderlei	Presidente Prudente	SP	Brazil	19060-900
2	Universidade Estadual Paulista Júlio de Mesquita Filho	Presidente Prudente	São Paulo	Brazil	19060900

Sponsors and Collaborators

Universidade Estadual Paulista Júlio de Mesquita Filho

Investigators

Study Director: Luiz Carlos M Vanderlei, Professor, Universidade Estadual Paulista - FCT/UNESP

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

Publications

None provided.

Responsible Party:

Luiz Carlos Marques Vanderlei, Professor, Universidade Estadual Paulista Júlio de Mesquita Filho

ClinicalTrials.gov Identifier:

NCT04569617

Other Study ID Numbers:

34303014.6.0000.5515

First Posted:

Sep 30, 2020

Last Update Posted:

Sep 30, 2020

Last Verified:

Sep 1, 2020

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Luiz Carlos Marques Vanderlei, Professor, Universidade Estadual Paulista Júlio de Mesquita Filho

Study Results

No Results Posted as of Sep 30, 2020