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Retinal Nerve Fiber Layer Thickness Analysis With Cirrus HD OCT Versus Stratus Optical Coherence Tomography (OCT)

Sponsor
Yonsei University (Other)
Overall Status
Unknown status
CT.gov ID
NCT00766389
Collaborator
(none)
200
Enrollment
1
Location
4
Duration (Months)
49.5
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The Cirrus HD OCT, a new spectral domain optical coherence tomography (OCT), has better resolution than the previous time domain Stratus OCT. Discriminating ability of these two OCTs for diagnosis of glaucoma and judgement of disease progression will be studied.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The Cirrus HD OCT is a new spectral domain OCT. Even though its resolution and speed are much better than the previous time domain Stratus OCT, its diagnostic power for glaucoma detection and judgement of disease progression should be directly compared with Stratus OCT. In the present study, we will review the data of peripapillary retinal nerve fiber layer thickness measurement using the Cirrus HD OCT and Stratus OCT. Their discriminating ability for diagnosis of glaucoma and judgement of disease progression will be compared using the ROC curves and Cohen's kappa.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    200 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Retrospective
    Official Title:
    Retinal Nerve Fiber Layer Thickness Analysis With Cirrus HD OCT Versus Stratus OCT
    Study Start Date :
    Oct 1, 2008
    Anticipated Primary Completion Date :
    Dec 1, 2008
    Anticipated Study Completion Date :
    Feb 1, 2009

    Arms and Interventions

    Arm Intervention/Treatment
    1

    Defined glaucoma patients
    2

    Glaucoma suspects and normal controls

    Outcome Measures

    Primary Outcome Measures

    1. Retinal nerve fiber layer thickness [When the OCT images are taking]

    Secondary Outcome Measures

    1. Visual field [When the OCT images are taking]

    2. Red-free fundus photo [When the OCT images are taking]

    3. Intraocular pressure [When the OCT images are taking]

    4. Central corneal thickness [When the OCT images are taking]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years to 80 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Retinal nerve fiber layer analysis with Cirrus OCT and Stratus OCT within 1 month
    Exclusion Criteria:

    • Intraocular surgeries history

    • DM

    • High refractive error ( < -4.00 diopters, or > + 4.00 diopters)

    • Media opacity

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Gong Je Seong Seoul Korea, Republic of 135-720

    Sponsors and Collaborators

    • Yonsei University

    Investigators

    • Study Chair: Gong Je Seong, MD, PhD, Yonsei University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00766389
    Other Study ID Numbers:
    • 3-2008-0113
    First Posted:
    Oct 6, 2008
    Last Update Posted:
    Oct 6, 2008
    Last Verified:
    Oct 1, 2008
    Keywords provided by , ,
    Glaucoma
    Retinal nerve fiber layer
    Cirrus OCT
    Stratus OCT
    Additional relevant MeSH terms:
    Glaucoma

    Study Results

    No Results Posted as of Oct 6, 2008