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Retinal Nerve Fiber Layer Thickness Measurement on Parapapillary Atrophy With the Cirrus High-Definition (HD) Optical Coherence Tomography (OCT)

Sponsor
Yonsei University (Other)
Overall Status
Unknown status
CT.gov ID
NCT00742196
Collaborator
(none)
30
Enrollment
1
Location
5.9
Duration (Months)
5
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Retinal nerve fiber layer (RNFL) thickness measurement on the parapapillary atrophy is incorrect. Because a new spectral domain OCT, the Cirrus HD OCT, uses a movable circle to analyze the RNFL thickness, we may suggest a new analysis strategy for the parapapillary atrophy.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Recently, the retinal nerve fiber layer (RNFL) thickness measurement using the optical coherence tomography (OCT) becomes very useful to detect such a glaucomatous damage. However, there are some difficult cases including parapapillary atrophy to perform this measurement. Because the RNFL thickness is so sensitive to the position of measurement and the measurement of RNFL thickness on parapapillary atrophy is incorrect, it is difficult to determine exact RNFL thickness in patients with a large parapapillary atrophy. In the present study, we want to find the proper method to analyze the RNFL thickness on parapapillary atrophy. The previous OCT used a fixed circle to measure the RNFL thickness, but the new spectral domain OCT, the Cirrus HD OCT, uses a movable one. Therefore, we may suggest a new analysis strategy for the parapapillary atrophy.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    30 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Retrospective
    Official Title:
    Retinal Nerve Fiber Layer Thickness Measurement on Parapapillary Atrophy With
    Study Start Date :
    Sep 1, 2008
    Anticipated Primary Completion Date :
    Dec 1, 2008
    Anticipated Study Completion Date :
    Mar 1, 2009

    Arms and Interventions

    Arm Intervention/Treatment
    1

    No parapapillary atrophy
    2

    Parapapillary atrophy

    Outcome Measures

    Primary Outcome Measures

    1. Retinal nerve fiber layer thickness [when the OCT images are taking]

    2. Size of parapapillary atrophy [when the OCT images are taking]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 70 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Qualified OCT images (signal strength > or = 8)
    Exclusion Criteria:

    • Previous intraocular surgery history

    • Media opacity

    • DM

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Gong Je Seong Seoul Korea, Republic of 135-720

    Sponsors and Collaborators

    • Yonsei University

    Investigators

    • Principal Investigator: Gong Je Seong, MD, PhD, Yonsei University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00742196
    Other Study ID Numbers:
    • 3-2008-0076-2
    First Posted:
    Aug 27, 2008
    Last Update Posted:
    Aug 27, 2008
    Last Verified:
    Aug 1, 2008
    Keywords provided by , ,
    Parapapillary atrophy
    Retinal nerve fiber layer thickness
    Glaucoma
    Cirrus OCT
    Additional relevant MeSH terms:
    Glaucoma
    Atrophy

    Study Results

    No Results Posted as of Aug 27, 2008