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Retrospective Study of the Protective Effect of Gastrodin on Myocardium in Patients Undergoing Cardiac Surgery

Sponsor
Wuhan Union Hospital, China (Other)
Overall Status
Completed
CT.gov ID
NCT06012994
Collaborator
(none)
160
Enrollment
1
Location
56
Actual Duration (Months)
2.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Retrospective collection of Wuhan Union hospital from December 1,2018 to June 30,2021 to meet the entry and discharge standards. The patient 's medical record data were divided into study group and control group according to the use of gastrodin during operation. The perioperative data and prognostic outcomes in the patient 's medical records were collected and analyzed. The degree of myocardial injury and postoperative clinical outcomes were compared between the two groups.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    160 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Retrospective Study of the Protective Effect of Gastrodin on Myocardium in Patients Undergoing Cardiac Surgery
    Actual Study Start Date :
    Dec 1, 2018
    Actual Primary Completion Date :
    Jun 30, 2021
    Actual Study Completion Date :
    Jul 31, 2023

    Arms and Interventions

    Arm Intervention/Treatment
    GAS
    Control

    Outcome Measures

    Primary Outcome Measures

    1. The degree of myocardial injury [The myocardial tissue was collected during the operation. About 2 hours on average]

      The myocardial tissue trimmed by the surgeon according to the surgical requirements was collected during the operation for electron microscopy observation and detection of related molecular content.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Patients agedā‰„18 years, regardless of gender;

    • Patients undergoing elective cardiac surgery under general anesthesia;

    • ASA grade 1 ~ 3.

    Exclusion Criteria:

    • Suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.);

    • Moderate to severe malnutrition, moderate to severe anemia;

    • Persistent infection;

    • Severe preoperative underlying diseases (such as severe liver and kidney dysfunction)

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China 430022

    Sponsors and Collaborators

    • Wuhan Union Hospital, China

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Wuhan Union Hospital, China
    ClinicalTrials.gov Identifier:
    NCT06012994
    Other Study ID Numbers:
    • mzk202303
    First Posted:
    Aug 28, 2023
    Last Update Posted:
    Aug 28, 2023
    Last Verified:
    Aug 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No

    Study Results

    No Results Posted as of Aug 28, 2023