The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Sponsor
Sisli Hamidiye Etfal Training and Research Hospital (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05999266
Collaborator
(none)
100
1.5

Study Details

Study Description

Brief Summary

The knee pain status of the patients who are followed in the rheumatology special branch of the Physical Medicine and Rehabilitation Outpatient Clinic and who meet the inclusion criteria will be questioned. In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. The physician who performed the ultrasonographic measurements of the knee pain status of the patients does not know.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Ultrasonographic Measurements

Study Design

Study Type:
Observational [Patient Registry]
Anticipated Enrollment :
100 participants
Observational Model:
Case-Only
Time Perspective:
Cross-Sectional
Official Title:
The Effect of Ultrasonographic Cartilage Thickness and Quadriceps/Hamstring Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis
Anticipated Study Start Date :
Aug 15, 2023
Anticipated Primary Completion Date :
Sep 15, 2023
Anticipated Study Completion Date :
Sep 30, 2023

Arms and Interventions

Arm Intervention/Treatment
Rheumatoid Arthritis Patients with Knee Pain

In patients with knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Diagnostic Test: Ultrasonographic Measurements
In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Rheumatoid Arthritis Patients without Knee Pain

In patients without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Diagnostic Test: Ultrasonographic Measurements
In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Outcome Measures

Primary Outcome Measures

  1. Ultrasonographic Cartilage Thickness Measurement [through study completion, an average of 1 month]

    Tibial cartilage thickness will be visualized by ultrasound with the knee held in 30 degrees of flexion, and 3 measurements will be taken from the medial, lateral and midline.

  2. Ultrasonographic Muscle Measurement Thickness Measurement [through study completion, an average of 1 month]

    The quadriceps muscle thickness will be measured by determining the midpoint between the SIAS and the patella while the patient is lying in the supine position. Hamstring muscle thickness will be measured at the intersection of a line drawn at 60% distal between the greater trochanter and the outer femoral condyle, and at the midline of the popliteal fossa, with the patient lying on the prone. These 2 measurements will be proportional to each other.

Eligibility Criteria

Criteria

Ages Eligible for Study:
30 Years to 50 Years
Sexes Eligible for Study:
Female
Inclusion Criteria:
  • Rheumatoid Arthritis > Diagnosed for 1 year

  • -Female gender

  • -The patient has been in remission or low disease activity for at least 3 months

  • -Be able to ambulatory

  • -No significant deformity in the lower extremity joints

Exclusion Criteria:
  • Patient with active arthritis or high disease activity

    • Significant deformity of the lower extremity joints and inability to ambulate
  • -Pregnant patient

    • Presence of malignancy
    • Patient with a severe psychiatric disorder and difficulty in cooperation
    • Presence of cardiovascular and pulmonary comorbidities that will prevent exercise
  • -Male gender

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Sisli Hamidiye Etfal Training and Research Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Aylin Ayyıldız, Medical Doctor, Sisli Hamidiye Etfal Training and Research Hospital
ClinicalTrials.gov Identifier:
NCT05999266
Other Study ID Numbers:
  • 15082023
First Posted:
Aug 21, 2023
Last Update Posted:
Aug 21, 2023
Last Verified:
Aug 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Aug 21, 2023