Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Study Details
Study Description
Brief Summary
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology. We planned to compare the patients by recording preoperative and postoperative ECGs. We also planned to record the patients' intraoperative blood pressure, saturation, and pulse rate, rickeragitation scale, and vas score.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
| N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Effects of Dexmetomidine Patients in this group will be given dexmedetomidine infusion during the intraoperative period to provide controlled hypotension. |
Drug: Dexmedetomidine
After the induction of general anesthesia, one group (Group: 1) will be administered dexmedotomidin infizyon and group (Group :2)remifentanil
|
| Active Comparator: Effects of Remifentanil Patients in this group will be given remifentanil infusion during the intraoperative period to provide controlled hypotension. |
Drug: Remifentanil
Remifentanil
|
Outcome Measures
Primary Outcome Measures
- iceb [preoperative and postoperative (immediatly after extubation)]
Qt\Qrs
Secondary Outcome Measures
- Riker Agitation Scale [Immediately after extubation]
7 -Dangerous Agitation, 6 - Very Agitated, 5 - Agitated, 4 - Calm and Cooperative, 3 - sedated, 2- Very Sedated, 1 -Unarousable
- mean arterial pressure [when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion]
mmHg
- heart rate [when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion]
beats\minute
- Numeric Rating Scale [Postoperative 0-2 hours]
They will be numbered from 1 to 10. 1 mildest 10 most severe pain
Eligibility Criteria
Criteria
Inclusion Criteria:
- patients with an ASA score of I and between the ages of 17-45 years, who were to undergo general anesthesia with sevofulurane were included in the study.
Exclusion Criteria:
Patients aged <17 and >45 years, patients with liver and/or kidney failure, obese patients (BMI >30), trauma patients, ASA II-III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study.
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Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- HTosun