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Risk Assessment Tool for Graft Survival in Pediatric Kidney Transplantation

Sponsor
Radboud University Medical Center (Other)
Overall Status
Completed
CT.gov ID
NCT05388955
Collaborator
(none)
1,415
Enrollment
666
Actual Duration (Months)

Study Details

Study Description

Brief Summary

Registry study in which data of all pediatric kidney recipients in the Netherlands (registered in the Nederlandse Orgaan Transplantatie Registry) are studied to develop a risk calculator for graft loss.

Condition or Disease Intervention/Treatment Phase
  • Other: None, transplantation recipients

Detailed Description

The pre-transplantation parameters of all recipients are used to do a multivariable regression analysis.

The B-coefficients of this analysis will be used to develop a risk calculator that predicts graft survival after transplantation per year of transplantation.

Study Design

Study Type:
Observational
Actual Enrollment :
1415 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
A Pre-transplantation Risk Assessment Tool for Graft Survival After Pediatric Kidney Transplantation Based on a Dutch Cohort
Actual Study Start Date :
Jan 1, 1966
Actual Primary Completion Date :
Jul 1, 2021
Actual Study Completion Date :
Jul 1, 2021

Outcome Measures

Primary Outcome Measures

  1. Graft survival [Up to 50 years after transplantation]

    Functioning graft of death with functioning graft. Survival graph: Percentage recipients with a functioning graft over time

Eligibility Criteria

Criteria

Ages Eligible for Study:
0 Years to 18 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:

Pediatric kidney recipients

  • transplantation in the Netherlands

  • signed informed consent

Exclusion Criteria:

  • combined transplantation (pancreas-kidney of liver-kidney transplantation)

  • No informed consent

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Radboud University Medical Center

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Radboud University Medical Center
ClinicalTrials.gov Identifier:
NCT05388955
Other Study ID Numbers:
  • Riskcalculator.Pediatric.ntx
First Posted:
May 24, 2022
Last Update Posted:
May 31, 2022
Last Verified:
May 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Kidney Diseases

Study Results

No Results Posted as of May 31, 2022