DeTaPoP: Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines

Sponsor

Centre Médical Porte Verte (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT06042972

Collaborator

(none)

800

Enrollment

Location

Anticipated Duration (Months)

88.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the Patient Heath Questionnaire 2 (PHQ2) and evaluate the factors that could be linked to it.

Condition or Disease	Intervention/Treatment	Phase
Post Partum Depression	Other: Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables

Detailed Description

The majority of studies and literature on maternal psychology focus on mothers of infants and newborns. The psychological experience of mothers with older children is still yet to be one of the subjects covered in the research on maternal psychology.

Postpartum depression characterizes itself in a depressive episode without psychotic characteristics, where symptoms appear in the year following delivery.

These symptoms reach their peak between 3 and 6 weeks postpartum. The diagnosis of postpartum depression is made by health professionals with the help of questionnaires such as the Edinburgh Postnatal Depression Scale (EPDS) or the Patient Health Questionnaire 2 (PHQ2).

According to the last national perinatal survey from Santé Publique France (Edition 2021), the rate of women having postpartum depression was estimated at 16.7%.

In France, the current psychological follow-up exam for women after giving birth includes a postnatal interview which is systematically offered between the 4th and the 8th week after delivery. It can be followed by another interview between the 10th and 14th week postpartum if judged necessary by the healthcare provider. It can also be offered by request.

Currently, there are no screening consultations for postpartum depression beyond the 14th week postpartum. Health care professionals are trained to be vigilant in the 1st year postpartum but not beyond this time frame.

A multicentric Australian study based on 1,507 women described the prevalence of maternal depression from early pregnancy to 4 years postpartum. It also covered the risk factors for depressive symptoms at 4 years postpartum.

The study concluded that maternal depression is more common at 4 years postpartum than at any time in the first 12 months postpartum. The prevalence of depressive symptoms at 4 years postpartum was 14.5% which was higher than at any time-point in the first 12 months post partum.

Currently, no French study focuses on the number of women suffering from maternal depression beyond 12 months postpartum.

This study aims to assess the prevalence of women 1 to 4 years postpartum who are suspected to have maternal depression and its linked factors.

Depression in one's lifetime can lead to negative consequences on a mother's psychological health and her quality of life, as well as her children's health.

The impact on children can include physical or mental developmental delay, regressed cognitive or language development, and general infant health issues.

Thus, if this study shows a significant risk for women to develop delayed maternal depression, extending a psychological follow-up exam of women beyond the 1st year postpartum could be necessary.

Moreover, screening and treating these women could limit the consequences on their children's development and well-being.

Study Design

Study Type:

Observational

Anticipated Enrollment :

800 participants

Observational Model:

Other

Time Perspective:

Prospective

Official Title:

Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines

Anticipated Study Start Date :

Sep 30, 2023

Anticipated Primary Completion Date :

Sep 30, 2023

Anticipated Study Completion Date :

Jun 30, 2024

Outcome Measures

Primary Outcome Measures

Edinburgh Postnatal Depression Scale and Patient Health Questionnaire 2 [Through study completion, an average of 10 months]
The primary outcome is positive if the Edinburgh Postnatal Depression Scale (EPDS) or the Patient Health Questionnaire 2 (PHQ2) are positive, meaning a score superior or equal to 10.5 for the EPDS or a score superior or equal to 3 for the PHQ2

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Women over 18 years old
Women from 1 year to 4 years postpartum or having children aged from 1 to 4 years old
Patient gave their consent to participate in the study
Patient lives in Yvelines
Patient speaks and understands French
Patient reads and writes in French

Exclusion Criteria:

Patient suffered from postpartum depression in the 1st year after giving birth or is currently being treated for postpartum depression that started showing symptoms in the 1st year after giving birth.
Patient is currently pregnant
Patient gave birth less than 1 year prior or more than 4 years prior; or has a child who is less than one year old; or 5 or more years old
Patient didn't give her consent to participate in the study
Patient is under guardianship or judicial safeguard