Risk Factors for Refeeding Syndrome in the Surgical Intensive Care Unit
Study Details
Study Description
Brief Summary
Refeeding Syndrome is a condition that occurs when patients who are undernourished or undernourished suddenly start overfeeding, causing electrolyte disturbances and vitamin deficiencies, resulting in neurological and cardiac problems. It may even result in death. It is aimed to prevent the development of Refeeding Syndrome with nutrition in accordance with the guidelines. The aim of this study is to determine the risk factors for Refeeding Syndrome in Intensive Care Unit (ICU).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Nutritional support is an important part of treatment in intensive care patients. Especially existing comorbidities and developing acute problems before intensive care admission can cause serious malnutrition for patients. Refeeding syndrome is a serious, life-threatening condition accompanied by electrolyte and metabolic disorders as a result of rapid re-feeding following prolonged starvation or malnutrition. The condition may be accompanied by electrolyte disorders such as hypophosphatemia, hypokalemia and hypomagnesemia, as well as decrease in vitamin levels (especially vitamin B1), fluid imbalance and salt retention. The resulting imbalances can cause cardiac and neurological side effects, impaired organ functions and even death. The refeeding protocol should be individualized to each patient's clinical situation. In this study, although nutritional protocols in accordance with the guidelines are applied in patients with risk factors for the development of Refeeding Syndrome, whether Refeeding Syndrome develops and the facilitating factors will be investigated in ICU.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| the treated patients in ICU Patients receiving nutrition while receiving treatment in intensive care |
Other: Refeeding Syndrome
Patients who developed Refeeding Syndrome despite proper nutrition while receiving treatment in the ICU
|
Outcome Measures
Primary Outcome Measures
- Occurrence of Refeeding Syndrome [from june 9, 2023 to june 9, 2024]
Occurrence of RFS：Within 72 hours after feeding serum phosphorus < 0.0.87mmol/L, or from the baseline levels drop > 0.16% or drop > 30%;And (or) hypokalemia, hypomagnesemia, hypocalcemia and corresponding clinical symptoms
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patients are intensive care patients
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Patients' age > 18 -
Exclusion Criteria:
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Diabetic ketoacidosis
-
Other risk factors for hypophosphatemia (patients on continuous hemodialysis, hyperphosphatemia treatment, parathyroidectomy)
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Patients with pre-study hypophosphatemia (< 0.65 mmol/L)
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Patients with hyperparathyroidism
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Terminal stage cancer patients
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Patients with Glasgow Coma Scale ≤5
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Patients with respiratory and metabolic alkalosis -
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Şerife Seçgin | Samsun | Turkey | 55270 |
Sponsors and Collaborators
- Samsun University
Investigators
- Study Director: ÖZGÜR KÖMÜRCÜ, SAMSUN UNIVERSITY HOSPITAL
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- SÜKAEK-2023 12/20