EUROCOV: Risk Stratification of Patients With Suspected COVID-19 Presenting to the ED

Sponsor

European Society for Emergency Medicine (EUSEM) Research Network (Other)

Overall Status

Enrolling by invitation

CT.gov ID

NCT04682093

Collaborator

(none)

8,000

Enrollment

Locations

11.7

Anticipated Duration (Months)

1600

Patients Per Site

136.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This project is an unfunded collaboration of approximately 30 emergency departments across Europe led by the EUSEM research network. It involves collection of data in relation to determining the epidemiology and outcome of adult patients who present to emergency departments with a suspected Covid infection.

Condition or Disease	Intervention/Treatment	Phase
Covid19

Detailed Description

Over the past 6 months, the world has faced a novel infection disease outbreak, due to a novel coronavirus, the severe acute respiratory syndrome coronavirus (SARS-CoV2), with a massive impact on healthcare resource.

In Europe, numbers of confirmed cases continue to rise. Europe is currently one of the regions with the highest number of Covid-19 cases and deaths due to this emergent diseases.

Most COVID-19 infected patients present with mild to moderate acute respiratory symptoms, including cough, fever, dyspnea and pneumonia. About 20% will present with severe or critical manifestations of the disease, including pneumonia, respiratory failure and acute respiratory distress syndrome (ARDS).

Anticipating the needs for hospitalization in ward and/or intensive care is crucial.

Emergency departments are at the front line for triaging patients with suspected Covid-19 and referring them to the appropriate level of care.

In Europe, the number of ED patients with suspected Covid-19 is variable; rate of hospitalization from ED reaches 40% for this population.

Risk stratification and management decisions of patients presenting to the ED with suspected COVID-19 is a challenge for emergency physicians.

Study Design

Study Type:

Observational

Anticipated Enrollment :

8000 participants

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Risk Stratification of Patients With Suspected COVID-19 Presenting to the ED (EUROCOV Study)

Actual Study Start Date :

Mar 9, 2020

Anticipated Primary Completion Date :

Jan 31, 2021

Anticipated Study Completion Date :

Feb 28, 2021

Outcome Measures

Primary Outcome Measures

hospitalization [30 days]
hospitalization after ED visit
length of hospital stay [30 days]
Hospital LOS
in-hospital mortality [30 days]
Death during hospitalization
ICU admission [30 days]
ICU admission after ED visit

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 130 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Adult patients (>= 18 years old) attending the ED with a clinical suspicion of COVID-19 based on the presence of the following criteria
Fever >= 38 °C
respiratory symptoms (dyspnea, cough, expectorations)
any other symptoms suggestive of COVID-19 including digestive signs (diarrhea, anosmia…)

Exclusion Criteria:

None

Contacts and Locations

Locations

	Site	City	Country
1	EUSEM RN Country lead	Zagreb	Croatia
2	EUSEM RN Country lead	Hämeenlinna	Finland
3	EUSEM RN Country lead	Tours	France
4	EUSEM RN Country lead	Athens	Greece
5	EUSEM RN Country lead	Forlì	Italy