RLIP76 in Human Serum in Adults With Rheumatologic Diseases
Sponsor
University of North Texas Health Science Center (Other)
Overall Status
Withdrawn
CT.gov ID
NCT00861159
Collaborator
(none)
100
1
Study Details
Study Description
Brief Summary
It is the investigators aim to determine the feasibility of directly detecting anti-RLIP76 auto-antibodies in human serum using prepared RLIP76 antigen peptides in persons with rheumatologic disease and persons without rheumatologic diesease ("healthy subjects").
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Detailed Description
This is an exploratory study conducted to see the feasibility of measuring the anti-RLIP76 antibody and to standardize the methods for its measurement. We will perform these studies on blood samples obtained from human subjects after informed concent for blood draw for research purposes is obtained by the Clinical Research Co-ordinator (CRC).
Study Design
Study Type:
Observational
Anticipated Enrollment
:
100 participants
Observational Model:
Case-Only
Time Perspective:
Prospective
Official Title:
Measurement Of RLIP76 Auto Antibodies in Human Serum In Adults With Rheumatologic Diseases.
Study Start Date
:
Sep 1, 2011
Anticipated Primary Completion Date
:
Sep 1, 2011
Anticipated Study Completion Date
:
Sep 1, 2011
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| 1
|
Outcome Measures
Primary Outcome Measures
- The focus of the present study is limited to establishing validated protocols for detection of anti-RLIP76 antibodies in human sera. [three years]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- Adult (age 18+), non-pregnant subjects with previously diagnosed rheumatologic disease will be candidates for the study.
Exclusion Criteria:
- Children, pregnant women, prisoner, persons with any medical condition that precludes phlebotomy, and patients unwilling or unable to provide consent.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of North Texas Health Science Center | Fort Worth | Texas | United States | 76109 |
Sponsors and Collaborators
- University of North Texas Health Science Center
Investigators
- Principal Investigator: Sanjay Awasthi, MD, University of North Texas Health Science Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00861159
Other Study ID Numbers:
- 2008-31
First Posted:
Mar 13, 2009
Last Update Posted:
Jan 12, 2011
Last Verified:
Jan 1, 2011
Keywords provided by ,
,
Additional relevant MeSH terms: