pCND: The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

Sponsor

Assiut University (Other)

Overall Status

Unknown status

CT.gov ID

NCT04076514

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC). This study main goal is to investigate benefits of prophylactic central neck dissection in clinically node-negative papillary thyroid carcinoma.

Condition or Disease	Intervention/Treatment	Phase
Papillary Thyroid Cancer	Procedure: central neck dissection

Detailed Description

Papillary thyroid carcinoma (PTC) is the most common type of differentiated thyroid carcinoma. Recurrence rate is still high. The standard management is total thyroidectomy. regional lymph node metastasis is noted in recurrent cases. Some studies stated benefits of central neck dissection in orevention of recurrence and others said there is no benefits. so prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC).

Study Design

Study Type:

Observational

Anticipated Enrollment :

20 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

Anticipated Study Start Date :

Sep 1, 2020

Anticipated Primary Completion Date :

Sep 30, 2020

Anticipated Study Completion Date :

Nov 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
patients with node negative papillary thyroid carcinoma	Procedure: central neck dissection dissection of central cervical lymph node grope in low grade papillary thyroid cancer

Arm

Intervention/Treatment

patients with node negative papillary thyroid carcinoma

Procedure: central neck dissection

dissection of central cervical lymph node grope in low grade papillary thyroid cancer

Outcome Measures

Primary Outcome Measures

the incidence metastatic lymph node in patients with clinically node-negative thyroid carcinoma who underwent total thyroidectomy with central neck dissection [12 months]
numbers of positive histopathological lymph node biopsies postoperative

Eligibility Criteria

Criteria

Ages Eligible for Study:

16 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

patients with papillary thyroid cancer with clinically node negative.

Exclusion Criteria:

patients with clinical evidence of nodal metastases.
patients with a previous history of thyroidectomy.
patients with mixed-type papillary thyroid cancer.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Ahmed Kamel	Asyūţ	Asyut	Egypt

Sponsors and Collaborators

Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Ahmed Kamel Ali, resident, Assiut University

ClinicalTrials.gov Identifier:

NCT04076514

Other Study ID Numbers:

Ahmed1712

First Posted:

Sep 3, 2019

Last Update Posted:

Jul 14, 2020

Last Verified:

Jul 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Thyroid Neoplasms

Thyroid Cancer, Papillary

Thyroid Diseases

Study Results

No Results Posted as of Jul 14, 2020