Role Of Transthoracic Ultrasound in Predicting Post-extubation Distress During Successful Weaning
Study Details
Study Description
Brief Summary
-To Assess Value of Transthoracic Ultrasound In Predicting Post-extubation Distress in Respiratory ICU Using Ultrasound Parameters As Diaphragmatic Excursion ,Diaphragmatic,Diaphragmatic Thickness Fraction,Diaphragmatic Thickness.
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Detailed Description
Establishing the correct time to extubate mechanically ventilated patients is a crucial issue in the critical care practice. Both premature and delayed extubation prolong the duration of mechanical ventilation and the intensive care unit (ICU) length of stay and increase morbidity and mortality. Therefore, accurate prediction of post-extubation distress and the early diagnosis of the causes responsible for failure of a trial of pressure support ventilation or a trial of totally unsupported respiration are of paramount importance to improve the outcome of mechanically ventilated patients in the ICU.
The Investigators hypothesized that the use of an integrative thoracic ultrasound assessment, encompassing bedside respiratory, and diaphragm sonographic data, could accurately predict post-extubation distress in patients who succeeded in a pressure support ventilation trial. In addition, The Investigators suggest that the use of appropriate analytical methods, that is, machine-learning methods, could permit the evaluation of the specific impact of respiratory and diaphragm sonographic data on the final estimation of a likelihood of post-extubation distress .
Study Design
Outcome Measures
Primary Outcome Measures
- post-extubation distress ["through study completion, an average of 3 year".]
Using Transthoracic US to measure Diaphragmatic Excursion and Diaphragmatic Thickness as Predictors of Postextubation Distress during Successful Weaning Trials.
Secondary Outcome Measures
- Evaluation of different factors that affect weaning outcome as diaphragmatic dysfunction,ventilator associated pneumonia,electrolyte disturbances and so on. [Doing Transthoracic US 48 hour after Starting of Mechanical Ventilation when Patient becomes Weanable during Weaning Trials,and 48 hour Postextubation Weaning and 48 hour postextubation.]
Looking on Diaphragmatic function And If There is any Ventilator Associated pneumonia And Electrolyte Disturbance
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients above 18 yrs. old who admitted to respiratory ICU and mechanically ventilated due to chest diseases and passed weaning trials
Exclusion Criteria:
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Pregnancy.
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Neuromuscular disorders.
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Psychiatric instability.
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Uncontrolled cardiovascular disease.
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Tracheostomy.
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patints with failed weaning trials.
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Inability to provide informed consent.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
- Study Director: Hoda Ahmad Ali, prof, Respiratory ICU of Assiut University Hospital
- Study Director: Ali Abdelazeem Hassan, prof, Respiratory ICU of Assiut University Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- Transthoracic US