Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study
Sponsor
Cairo University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05607251
Collaborator
(none)
21
3
Study Details
Study Description
Brief Summary
Aim of the study:
-
Assess the correlation between salivary alkaline phosphatase levels and dental caries.
-
Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme.
-
Assess the effect of growth of children on caries experience and severity.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
21 participants
Observational Model:
Other
Time Perspective:
Cross-Sectional
Official Title:
Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study
Anticipated Study Start Date
:
Jan 1, 2023
Anticipated Primary Completion Date
:
Mar 1, 2023
Anticipated Study Completion Date
:
Apr 1, 2023
Outcome Measures
Primary Outcome Measures
- Salivary Alkaline Phosphatase levels in children with and without dental caries [2 months]
Measured by spectrophotometry (unit: U/L)
Secondary Outcome Measures
- Caries index [2 months]
Measured by DMFT and deft (unit: scores)
- Caries severity [2 months]
Measured by ICDAS (unit: scores)
Eligibility Criteria
Criteria
Ages Eligible for Study:
6 Years
to 8 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
-
Children aged 6 to 8 years old.
-
Children with and without previous dental visits.
Exclusion Criteria:
-
Children with any systemic or mental illness.
-
Children whose parents refuse to sign the informed consent.
-
Children who will not cooperate on participation
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Cairo University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Salma Ahmed Abdelrahman,
General Dentist,
Cairo University
ClinicalTrials.gov Identifier:
NCT05607251
Other Study ID Numbers:
- CUP1/11/2022
First Posted:
Nov 7, 2022
Last Update Posted:
Nov 7, 2022
Last Verified:
Nov 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: