Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome
Study Details
Study Description
Brief Summary
Burning mouth syndrome is an idiopathic condition characterized by symptoms burning and / or pain of the oral mucosa with an orderly clinical finding. So far not found a unique way of treatment. It is a diagnosis that impairs the quality of life of patients, and consequently it can affect the quality of sleep. Melatonin is a hormone secreted from pineal gland and regulates the day-night rhythm of man, and whose production in the body decreases aging. The level of melatonin in saliva correlates well with the level of melatonin in plasma, therefore they are advantages of determining from saliva painlessness and non-invasiveness of the procedure itself. The purpose of this study was to compare the level of melatonin in saliva and the quality of sleep with help of the Epworth Sleepiness Scale in patients with burning mouth syndrome and control groups of patients without subjective oral disorders and with an orderly clinical finding.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Study group Female patients of the Department of Oral medicine diagnosed with burning mouth syndrome |
Other: Epworth's sleepiness scale; unstimulated saliva sample
Unstimulated saliva sample; Epworth's sleepiness scale
|
| Control group Age-matched female patients without oral lesions and without burning mouth syndrome |
Other: Epworth's sleepiness scale; unstimulated saliva sample
Unstimulated saliva sample; Epworth's sleepiness scale
|
Outcome Measures
Primary Outcome Measures
- determining the level of salivary melatonin [January 2021-July 2021]
The level of salivary melatonin will be determined in frozen samples of unstimulated saliva samples
Secondary Outcome Measures
- determining the difference in Epworth's sleepiness scale [January 2021-July 2021]
The test is a list of eight situations in which you rate your tendency to become sleepy on a scale of 0, no chance of dozing, to 3, high chance of dozing. Total score is graded from 0-24. 0-7:It is unlikely that you are abnormally sleepy. 8-9:You have an average amount of daytime sleepiness. 10-15:You may be excessively sleepy depending on the situation. You may want to consider seeking medical attention. 16-24:You are excessively sleepy and should consider seeking medical attention.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
female patients
-
primary burning mouth syndrome
-
without oral lesions
Exclusion Criteria:
-
secondary burning mouth syndrome
-
male gender
-
patients with oral lesions
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | School of Dental Medicine, University of Zagreb | Zagreb | Croatia | 10000 |
Sponsors and Collaborators
- University of Zagreb
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 09/2020