Leucine Supplementation in Elderly Men

• Sponsor: Maastricht University Medical Center (Other)
• Overall Status: Completed
• CT.gov ID: NCT00807508
• Collaborator: (none)
• Enrollment: 29
• Location: 1
• Arms: 2
• Duration (Months): 23
• Patients Per Site Per Month: 1.3

Study Details

Study Description

Brief Summary

In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men

Condition or Disease	Intervention/Treatment	Phase
Sarcopenia; Atrophy; Aging	Dietary Supplement: placebo; Dietary Supplement: leucine	Phase 1/Phase 2

Study Design

• Study Type: Interventional
• Actual Enrollment: 29 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Double
• Primary Purpose: Treatment
• Official Title: The Influence of Leucine Supplementation on Body Composition and Muscle Characteristics in Healthy Elderly
• Study Start Date: Jan 1, 2007
• Actual Primary Completion Date: Dec 1, 2007
• Actual Study Completion Date: Dec 1, 2008

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 1 daily leucine supplementation	Dietary Supplement: leucine; daily leucine capsules with each main meal
Placebo Comparator: 2 daily placebo supplementation	Dietary Supplement: placebo; wheat meal capsules with each main meal

Outcome Measures

Primary Outcome Measures

1. muscle mass and body composition [before and after 12 wk intervention]

Secondary Outcome Measures

1. muscle strength [before and after 12 wk intervention]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 65 Years to 85 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• living independently

Exclusion Criteria:

• Diabetes cardiovascular disease orthopedic limitations history of resistance training in past 5 years

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Maastricht University Medical Centre	Maastricht		Netherlands	6200 MD

Sponsors and Collaborators

• Maastricht University Medical Center

Investigators

• Principal Investigator: Luc JC van Loon, PhD, Maastricht University Medical Center

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00807508
• Other Study ID Numbers: MEC 06-3-062A
• First Posted: Dec 12, 2008
• Last Update Posted: Dec 12, 2008
• Last Verified: Dec 1, 2008

• Additional relevant MeSH terms: Sarcopenia

Study Results

No Results Posted as of Dec 12, 2008