Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study

Sponsor

Universidade do Algarve (Other)

Overall Status

Completed

CT.gov ID

NCT05918159

Collaborator

European Regional Development Fund (Other)

274

Enrollment

Location

45.3

Actual Duration (Months)

6.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal). Because muscle is metabolically active tissue, sarcopenia may also contribute to the development of some of the metabolic disorders associated with aging. However, the risk factors associated with sarcopenia are poorly understood. Thus, a cross-sectional survey of a sample of 274 elderly adults aged 60 or over, were included in the study. Correlations of sarcopenia with functional level, lipid and glycemic profile, nutritional and physical activity level, fall risk, quality of life, and self-reported comorbidities will be studied.

Condition or Disease	Intervention/Treatment	Phase
Sarcopenia Sarcopenic Obesity Frailty	Other: Sarcopenia Assessment

Study Design

Study Type:

Observational

Actual Enrollment :

274 participants

Observational Model:

Other

Time Perspective:

Cross-Sectional

Official Title:

Effects of Sarcopenia on the Fall Risk, Body Composition, General Health Status and Quality of Life in Elderly: a Population-based Study

Actual Study Start Date :

May 14, 2019

Actual Primary Completion Date :

Feb 20, 2023

Actual Study Completion Date :

Feb 20, 2023

Arms and Interventions

Arm	Intervention/Treatment
Elderly Group of 274 elderly	Other: Sarcopenia Assessment The prevalence of sarcopenia in a group of elderly people and its correlation with other health variables was determined.

Arm

Intervention/Treatment

Elderly

Group of 274 elderly

Other: Sarcopenia Assessment

The prevalence of sarcopenia in a group of elderly people and its correlation with other health variables was determined.

Outcome Measures

Primary Outcome Measures

Prevalence of Sarcopenia in elderly population [0 Months]
Determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region.
Quality of life in elderly population [0 Months]
Quality of life was assessed at one time point only (due to the nature of the cross-sectional study design) using a combination of semi-structured interviews and questionnaire SF-36-v2.

Secondary Outcome Measures

Cognitive Assessment [0 Months]
Cognitive Assessment was assessed by the instrument Montreal Cognitive Assessment (MoCA).
Body Composition in elderly population [0 Months]
Body composition was measured using the bioimpedance technique and the body mass index, fat mass, fat-free mass, muscle mass, total body water, resistance, reactance, phase angle and visceral fat were determined.
Lipid Profile in elderly [0 Months]
Lipid Profile was measured taking a sample blood which was analysed for apolipoproteins HDL, LDL, triglycerides and total cholesterol.
Glicemic Profile in elderly [0 Months]
Glicemic Profile was measured taking a sample blood which was analysed for Glycated Hemoglobin (HbA1c).
Inflammatory levels in elderly population [0 Months]
Inflammatory levels was measured taking a sample blood which was analysed for C-reactive protein - CRP.
Nutritional level in elderly population [0 Months]
Nutrional level was assessed at one time point only (due to the nature of the cross-sectional study design) using a combination of semi-structured interviews and a questionnaire Mini Nutritional Assessment.
Postural Stability in elderly population [0 Months]
Postural stability was assessed by a force platform using the length displacement of center of pressure.
Isokinetic muscle strength in elderly population [0 Months]
Isokinetic muscle strength of the quadriceps and hamstrings was measured by afixed dynamometer using peak torque, work, power, peak torque time and force.
Fall risk in elderly population [0 Months]
Fall risk was assessed by time up and go test and by The Modified Falls Efficacy Scale (MFES).
Physical Activity level in elderly population [0 Months]
Physical activity level was assessed at one time point only (due to the nature of the cross-sectional study design) using a combination of semi-structured interviews and questionnaire PASE - Physical Activity Scale for Elderly.
Impact of osteoarthritis on pain, stiffness and functionality in elderly population [0 Months]
Impact of osteoarthritis was assessed at one time point only (due to the nature of the cross-sectional study design) using a combination of semi-structured interviews and the questionnaire Womac Index.
Functional Level of Lower Limbs [0 Months]
To assess the functionality of the lower limbs, the Lower Extremity Functional Scale (LEFS) instrument was applied.
Handgrip strength (HGS) [0 Months]
HGS was measured with the handgrip Dynamometer Lafayette Digital 5030D1 in both upper limbs.
Identifies the concerns and priorities of older people [0 Months]
Following The World Health Organisation ICOPE guidelines, each assessment with ACT Assessment generates a report which lists identifies concerns and priorities for action, together with several summary scores to measure needs, risks and outcomes, including: Quality of life, Falls risk, Vision, Hearing, Activities of Daily Living, Nutrition, Locomotor, Oral Health, Accommodation, Finances, Cognition, Depression, Loneliness, Social participation, and Violence against older people.